Acivicin
[CAS# 42228-92-2]

Identification

• Name: Acivicin
• Synonyms: (2S)-2-Amino-2-[(5S)-3-Chloro-4,5-Dihydroisoxazol-5-Yl]Acetic Acid; (2S)-2-Amino-2-[(5S)-3-Chloro-4,5-Dihydro-1,2-Oxazol-5-Yl]Ethanoic Acid; At-125
• Molecular Formula: C₅H₇ClN₂O₃
• Molecular Weight: 178.57
• CAS Registry Number: 42228-92-2
• SMILES: [C@@H]1(ON=C(C1)Cl)[C@@H](C(O)=O)N
• InChI: 1S/C5H7ClN2O3/c6-3-1-2(11-8-3)4(7)5(9)10/h2,4H,1,7H2,(H,9,10)/t2-,4-/m0/s1
• InChIKey: QAWIHIJWNYOLBE-OKKQSCSOSA-N

Properties

• Density: 1.854g/cm³ (Cal.)
• Boiling point: 341.625°C at 760 mmHg (Cal.)
• Flash point: 160.41°C (Cal.)

References

• (1): Rodnina et al.. Selective compounds define Hsp90 as a major inhibitor of apoptosis in small cell lung cancer, Nature Chemical Biology, 2007