5-[Bis(2-chloroethyl)amino]-2,4(1H,3H)-pyrimidinedione
[CAS# 66-75-1]

Identification

• Classification: API >> Antineoplastic agents >> Alkylating agent
• Name: 5-[Bis(2-chloroethyl)amino]-2,4(1H,3H)-pyrimidinedione
• Synonyms: 5-N,N-Bis(2-chloroethyl)aminouracil; 5-[Bis(2-chloroethyl)amino]uracil; 5-[Di(beta-chloroethyl)amino]uracil; Aminouracil mustard; CB 4835; Chlorethaminacil; Demethyldopan; Desmethyldopan; ENT 50439; NCI C04820; NSC-34462; Nordopan; SK 19849; U-8344; Uracil mustard; Uracil nitrogen mustard; Uracillost; Uracilmostaza; Uramustin; Uramustine
• Molecular Formula: C₈H₁₁Cl₂N₃O₂
• Molecular Weight: 252.10
• CAS Registry Number: 66-75-1
• EC Number: 200-631-3

Properties

• Solubility: Very slightly soluble (0.17 g/L) (25 °C), Calc.^*
• Density: 1.44±0.1 g/cm³ (20 °C 760 Torr), Calc.^*
• Melting point: 206 °C (decomp)^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2017 ACD/Labs)

^** Lyttle, D. A.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin irritation	Skin Irrit.	2	H315
Serious eye damage	Eye Dam.	1	H318
Carcinogenicity	Carc.	2	H351
Acute toxicity	Acute Tox.	1	H300
Specific target organ toxicity - single exposure	STOT SE	3	H335