Chloramine-T trihydrate
[CAS# 7080-50-4]

Identification

• Classification: Analytical chemistry >> Analytical reagent >> Common analytical reagents
• Name: Chloramine-T trihydrate
• Synonyms: N-Chloro-p-toluenesulfonamide sodium salt trihydrate
• Molecular Formula: C₇H₇ClNNaO₂S.3(H₂O)
• Molecular Weight: 281.69
• CAS Registry Number: 7080-50-4
• EC Number: 615-172-8
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)[N-]Cl.O.O.O.[Na+]

Properties

• Melting point: 167-170 °C
• Flash point: 192 °C

Safety Data

• Hazard Symbols: GHS05;GHS07;GHS09 Danger
• Risk Statements: H302-H314-H318-H334-H3412
• Safety Statements: P233-P260-P264-P264+P265-P270-P271-P273-P280-P284-P301+P317-P301+P330+P331-P302+P361+P354-P304+P340-P305+P354+P338-P316-P317-P321-P330-P342+P316-P363-P403-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Respiratory sensitization	Resp. Sens.	1	H334
Skin corrosion	Skin Corr.	1B	H314
Serious eye damage	Eye Dam.	1	H318
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Skin corrosion	Skin Corr.	1C	H314

• Transport Information: UN 3263

Discovery and Applications

Chloramine-T trihydrate, chemically known as N-chloro-p-toluenesulfonamide trihydrate, was first synthesized in the early 20th century. It was developed by German chemist Walter Hempel and his colleagues with potential as a disinfectant and antiseptic. Chloramine-T has gained attention for its strong antimicrobial properties and effectiveness in a variety of applications, making it a valuable compound in the medical and industrial fields.

Chloramine-T trihydrate is widely used as a disinfectant and antiseptic. It is effective against a wide range of microorganisms, including bacteria, fungi, and viruses. In medical settings, it is used to disinfect surfaces, medical devices, and treat wounds. Its stability and effectiveness make it a reliable choice for infection control.

In water treatment, chloramine-T trihydrate is utilized for its ability to kill pathogens and purify water. It is used in municipal water systems and industrial processes to ensure water safety and quality. Its chlorinating properties help to effectively remove contaminants, making it a necessity for maintaining a clean water supply.

In veterinary medicine, chloramine-T trihydrate is used to treat animal infections. Its antimicrobial properties help control diseases and infections in livestock and pets. It is also used to disinfect animal housing and equipment, contributing to overall animal health and hygiene.

In industrial applications, Chloramine-T trihydrate is used as an oxidant and disinfectant in various manufacturing processes. It is used in the production of textiles, paper, and other materials where its disinfecting properties are of great benefit.

Chloramine-T trihydrate is used as a reagent and disinfectant in laboratories. It is used in biochemical analysis and research, where its antimicrobial properties help prevent contamination and maintain sterile conditions.

References

2022. Pretreatment Method for Chloramine-T Decon Sample Before GC Analysis of HD and VX. Bulletin of Environmental Contamination and Toxicology.
DOI: 10.1007/s00128-022-03612-5

1962. A new decomposition of serine and threonine by chloramine-T and periodate mixture. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
DOI: 10.1248/yakushi1947.82.4_503

1962. Microdetermination of nitrogen as indophenol blue by chloramine-T oxidation. Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
DOI: 10.1515/bchm2.1962.329.1.241