Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
[CAS# 82692-93-1]

Identification

• Classification: Biochemical >> Biochemical reagent >> Biological dye
• Name: Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
• Synonyms: 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt
• Molecular Formula: C₁₂H₁₈NNaO₄S
• Molecular Weight: 295.33
• CAS Registry Number: 82692-93-1
• EC Number: 617-377-8
• SMILES: CCN(CC(CS(=O)(=O)[O-])O)C1=CC=CC(=C1)C.[Na+]

Properties

• Solubility: 47mg/mL (DMSO)

Safety Data

• Hazard Symbols: GHS07 Warning
• Risk Statements: H302-H312-H332
• Safety Statements: P261-P264-P270-P271-P280-P301+P317-P302+P352-P304+P340-P317-P321-P330-P362+P364-P501

Discovery and Applications

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate, also known as SEMA3S, is a compound with important applications in various fields, mainly due to its unique chemical structure and properties. SEMA3S is characterized by a sulfonate group attached to a 2-hydroxypropane backbone with an N-ethyl-3-methylanilino moiety as a substituent. This structure confers several remarkable properties to the compound, including solubility in aqueous solutions and stability under various environmental conditions.

SEMA3S has attracted much attention in biomedical research, especially in studies related to cell signaling and neuronal development. Its ability to modulate cellular responses and interactions makes it valuable in exploring neural regeneration and guidance pathways.

Due to its biological activity and potential therapeutic benefits, SEMA3S is being investigated for pharmaceutical applications. Researchers are exploring its role in drug delivery systems, especially for neurological diseases, where guidance cues are critical for therapeutic efficacy.

In analytical chemistry, SEMA3S can be used as a standard reference material and calibrant. Its stable chemical properties make it suitable for spectroscopic and chromatographic analysis, helping to quantify and identify related compounds.

In addition to biological and pharmaceutical uses, SEMA3S can be used in a variety of industrial processes. It acts as a stabilizer and modifier in certain chemical reactions and formulations, helping to improve product quality and performance.

Ongoing research continues to explore additional applications and improvements for SEMA3S. Future advances may include customized modifications to enhance specific properties or functions, thereby expanding its reach across interdisciplinary fields.

References

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DOI: 10.1021/acs.langmuir.7b00308

2001. Acceleration of an Enzymatic Reaction in a Microchip. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 17(7).
DOI: 10.2116/analsci.17.809

2000. A liquid-stable reagent for lactic acid levels. Application to the Hitachi 911 and Beckman CX7. American Journal of Clinical Pathology, 114(1).
DOI: 10.1309/65uj-fq75-dvgc-xx1n