2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propanyl]acetamide
[CAS# 85666-84-8]

Identification

• Name: 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)-2-propanyl]acetamide
• Synonyms: "2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamide"; "Chloramphenicol, USP"; (R-(R*,R*))-2,2-Dichloro-N-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)acetamide
• Molecular Formula: C₁₁H₁₂Cl₂N₂O₅
• Molecular Weight: 323.13
• CAS Registry Number: 85666-84-8
• SMILES: C1=CC(=CC=C1[C@H]([C@@H](CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-]
• InChI: 1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1
• InChIKey: WIIZWVCIJKGZOK-RKDXNWHRSA-N

Properties

• Density: 1.5±0.1g/cm³ (Cal.)
• Melting point: 148-150°C (Expl.)
• Boiling point: 644.9±55.0°C at 760 mmHg (Cal.)
• Flash point: 343.8±31.5°C (Cal.)

Safety Data

• Safety Description: Harmful/Carcinogenic/Teratogenic/Light Sensitive

References

• (1): Morgane J. J. Moreau, Isabelle Morin and Patrick M. Schaeffer. Quantitative determination of protein stability and ligand binding using a green fluorescent protein reporter system, Mol. Biosyst., 2010, 6, 1285.