L-Norepinephrine bitartrate (CAS 108341-18-0) has a chemical story that connects molecular identity with practical chemistry. L-Norepinephrine bitartrate, CAS 108341-18-0, is the bitartrate monohydrate salt of norepinephrine, a principal endogenous catecholamine neurotransmitter and hormone. USP distinguishes this hydrated identity from anhydrous norepinephrine bitartrate. Norepinephrine strongly activates alpha-adrenergic receptors and also beta1 receptors. Intravenous norepinephrine is a foundational vasopressor for severe acute hypotension, including septic shock, because alpha-mediated vasoconstriction raises vascular tone. The salt form supports pharmaceutical formulation, while norepinephrine is the active species after dissolution. Its catechol ring is oxidation-sensitive, making formulation and storage chemistry important.
Its story also shows why synthesis and analytical control belong together: chemists must create the intended structure, distinguish it from process-related species and verify the form actually being handled.
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