L-Norepinephrine bitartrate (CAS 108341-18-0) has a chemical story that connects molecular identity with practical chemistry. L-Norepinephrine bitartrate, CAS 108341-18-0, is the bitartrate monohydrate salt of norepinephrine, a principal endogenous catecholamine neurotransmitter and hormone. USP distinguishes this hydrated identity from anhydrous norepinephrine bitartrate. Norepinephrine strongly activates alpha-adrenergic receptors and also beta1 receptors. Intravenous norepinephrine is a foundational vasopressor for severe acute hypotension, including septic shock, because alpha-mediated vasoconstriction raises vascular tone. The salt form supports pharmaceutical formulation, while norepinephrine is the active species after dissolution. Its catechol ring is oxidation-sensitive, making formulation and storage chemistry important.
The exact CAS identity matters because related salts, stereoisomers, intermediates and finished medicines can play very different roles even when their names look closely related.
Its story also shows why synthesis and analytical control belong together: chemists must create the intended structure, distinguish it from process-related species and verify the form actually being handled.
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