甘磷酸胆碱 GPC
[CAS# 28319-77-9]

基本信息

• 产品分类: 原料药 >> 神经系统用药 >> 拟胆碱药
• 产品名称: 甘磷酸胆碱 GPC
• 英文名: Choline glycerophosphate
• 别名: 2,3-Dihydroxypropyl 2-trimethylazaniumylethyl phosphate; 2-(((2,3-Dihydroxypropoxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium inner salt; L-alpha-Glycerylphosphorylcholine
• 分子式: C₈H₂₀NO₆P
• 分子量: 257.22
• CAS 登录号: 28319-77-9
• EC 号码: 248-962-2
• 分子行输入简码SMILES: C[N+](C)(C)CCOP(=O)([O-])OC[C@@H](CO)O

物理化学性质

• 溶解度: 10mM (水), 35 mg/mL (DMSO)

安全数据

• 危险品标志: GHS07 警告
• 危害标签: H315-H319-H335-H412
• 防护标签: P261-P273-P305+P351+P338

发现和应用

胆碱甘油磷酸盐 (CGP) 是一种化合物，因其在各个领域的多方面应用而备受关注。它是甘油磷酸盐和胆碱的衍生物，在细胞功能中起着至关重要的作用，在健康和工业领域具有一系列潜在应用。

参考文献

2025. Safety evaluation of alpha-glycerylphosphorylcholine as a novel food. Food and Chemical Toxicology, 195.
DOI: 10.1016/j.fct.2024.115123

2024. Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018. Nutrients, 16(21).
DOI: 10.3390/nu16213713

2024. Efficacy and safety of choline alphoscerate for amnestic mild cognitive impairment: a randomized double-blind placebo-controlled trial. BMC Geriatrics, 24(1).
DOI: 10.1186/s12877-024-05366-7