Lycopene
[CAS# 502-65-8]

Identification

• Classification: Food additive >> Color protection agent
• Name: Lycopene
• Molecular Formula: C₄₀H₅₆
• Molecular Weight: 536.88
• CAS Registry Number: 502-65-8
• EC Number: 207-949-1
• SMILES: CC(=CCC/C(=C/C=C/C(=C/C=C/C(=C/C=C/C=C(/C=C/C=C(/C=C/C=C(/CCC=C(C)C)C)C)C)/C)/C)/C)C

Properties

• Melting point: 172-173 °C

Discovery and Applications

Lycopene, a naturally occurring pigment responsible for the red color of tomatoes and other fruits, was first isolated and identified in the early 19th century. However, its structural elucidation was accomplished later in the 20th century, allowing for a deeper understanding of its properties and potential applications. Found abundantly in tomatoes, watermelons, and pink grapefruits, lycopene was initially recognized for its role as an antioxidant, protecting plants from oxidative damage. Its discovery paved the way for extensive research into its health benefits and applications in various industries.

Lycopene is widely used in nutritional supplements due to its antioxidant properties and potential health benefits. As a powerful antioxidant, it helps neutralize free radicals in the body, reducing oxidative stress and inflammation. Many people take lycopene supplements to support heart health, boost the immune system, and reduce the risk of chronic diseases such as cancer and cardiovascular diseases.

Lycopene is a popular ingredient in cosmetics and skincare products. Its antioxidant properties help protect the skin from environmental damage, UV radiation, and premature aging. Lycopene-based creams, lotions, and serums are used to improve skin texture, reduce wrinkles, and promote a youthful appearance. It is also incorporated into sunscreens for added protection against UV-induced skin damage.

Lycopene is widely used in the food industry as a natural colorant and flavor enhancer. It provides the vibrant red color to various food products, including sauces, soups, and beverages. As a natural pigment, lycopene is preferred over synthetic colorants in food formulations due to its perceived health benefits and clean label appeal. It also imparts a unique flavor profile, enhancing the taste of food products.

Lycopene has potential applications in pharmaceutical formulations due to its antioxidant and anti-inflammatory properties. It is being studied for its role in preventing and treating various health conditions, including cancer, cardiovascular diseases, and age-related macular degeneration. Lycopene supplements or lycopene-rich foods may be recommended as part of a holistic approach to disease prevention and management.

Lycopene is a subject of ongoing biomedical research to explore its potential therapeutic effects and mechanisms of action. Studies investigate its impact on cellular signaling pathways, gene expression, and disease progression. Researchers aim to elucidate how lycopene may contribute to the prevention and treatment of chronic diseases, paving the way for the development of novel therapies and interventions.

References

1998. Intestinal absorption of beta-carotene, lycopene and lutein in men and women following a standard meal: response curves in the triacylglycerol-rich lipoprotein fraction. The British journal of nutrition.
DOI: 10.1079/bjn19980026

1998. Lycopene: Chemistry, Biology, and Implications for Human Health and Disease. Nutrition Reviews.
DOI: 10.1111/j.1753-4887.1998.tb01691.x