Ethyl Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydro-3,5-Pyridinedicarboxylate
[CAS# 119945-59-4]

Identification

• Name: Ethyl Methyl 4-(2,3-Dichlorophenyl)-2,6-Dimethyl-1,4-Dihydro-3,5-Pyridinedicarboxylate
• Synonyms: (±) Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; (±)-Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate; (±)-Felodipine
• Molecular Formula: C₁₈H₁₉Cl₂NO₄
• Molecular Weight: 384.25
• CAS Registry Number: 119945-59-4
• SMILES: CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
• InChI: 1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
• InChIKey: RZTAMFZIAATZDJ-UHFFFAOYSA-N

Properties

• Density: 1.3±0.1g/cm³ (Cal.)
• Melting point: 144°C (Expl.)
• Boiling point: 471.5±45.0°C at 760 mmHg (Cal.)
• Flash point: 239.0±28.7°C (Cal.)
• Refractive index: 1.55 (Cal.)
• solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol

References

• (1): Umesh S. Kestur and Lynne S. Taylor. Role of polymer chemistry in influencing crystal growth rates from amorphous felodipine, CrystEngComm, 2010, 12, 2390.