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4-Ethyl-4-Hydroxy-3,4,12,14-Tetrahydro-1H-Pyrano[3'4':6,7]Indolizino[1,2-b]Quinoline-3,14-Dione
[CAS# 31456-25-4]

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Identification
Name 4-Ethyl-4-Hydroxy-3,4,12,14-Tetrahydro-1H-Pyrano[3'4':6,7]Indolizino[1,2-b]Quinoline-3,14-Dione
Synonyms (.+-.)-Camptothecin; 1H-Pyrano[3',4':6,7]Indolizino[1,2-B]Quinoline-3,14(4H,12H)-Dione-, 4-Ethyl-4-Hydroxy-, (+-)-; Camptothecin (+)-
Molecular Structure CAS#: 31456-25-4, 4-Ethyl-4-Hydroxy-3,4,12,14-Tetrahydro-1H-Pyrano[3'4':6,7]Indolizino[1,2-b]Quinoline-3,14-Dione
Molecular Formula C20H16N2O4
Molecular Weight 348.36
CAS Registry Number 31456-25-4
SMILES C2=C1C=CC=CC1=NC4=C2CN5C(C3=C(C(C(=O)OC3)(CC)O)C=C45)=O
InChI 1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3
InChIKey VSJKWCGYPAHWDS-UHFFFAOYSA-N
Properties
Density 1.513g/cm3 (Cal.)
Boiling point 757.01°C at 760 mmHg (Cal.)
Flash point 411.625°C (Cal.)
solubility Soluble to 5 mM in DMSO
References
(1) Strom, E. et al.. Small molecule inhibitor of p53 binding to mitochondria protects mice from gamma irradiation, Nature Chemical Biology, 2006
Market Analysis Reports
List of Reports Available for 4-Ethyl-4-Hydroxy-3,4,12,14-Tetrahydro-1H-Pyrano[3'4':6,7]Indolizino[1,2-b]Quinoline-3,14-Dione
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