8-Hydroxyguanosine
[CAS# 3868-31-3]

Identification

• Classification: Biochemical >> Nucleoside drugs >> Nucleoside intermediate
• Name: 8-Hydroxyguanosine
• Synonyms: 2-Amino-9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl]-3,7-Dihydropurine-6,8-Dione; 2-Amino-9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-2-Tetrahydrofuranyl]-3,7-Dihydropurine-6,8-Dione; 2-Amino-9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-Methylol-Tetrahydrofuran-2-Yl]-3,7-Dihydropurine-6,8-Quinone
• Molecular Formula: C₁₀H₁₃N₅O₆
• Molecular Weight: 299.24
• CAS Registry Number: 3868-31-3
• SMILES: [C@H]1(O[C@@H]([C@@H](O)[C@H]1O)CO)N2C3=C(NC2=O)C(=O)N=C(N3)N
• InChI: 1S/C10H13N5O6/c11-9-13-6-3(7(19)14-9)12-10(20)15(6)8-5(18)4(17)2(1-16)21-8/h2,4-5,8,16-18H,1H2,(H,12,20)(H3,11,13,14,19)/t2-,4-,5-,8-/m1/s1
• InChIKey: FPGSEBKFEJEOSA-UMMCILCDSA-N

Properties

• Density: 2.438g/cm³ (Cal.)

References

• (1): Aaron M. Fleming, James G. Muller, Insun Ji and Cynthia J. Burrows. Characterization of 2′-deoxyguanosine oxidation products observed in the Fenton-like system Cu(ii)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts, Org. Biomol. Chem., 2011, 9, 3338.