Prostaglandin D2
[CAS# 41598-07-6]

Identification

• Name: Prostaglandin D2
• Synonyms: (Z)-7-[(1R,2R,5S)-5-Hydroxy-2-[(E,3S)-3-Hydroxyoct-1-Enyl]-3-Oxo-Cyclopentyl]Hept-5-Enoic Acid; (Z)-7-[(1R,2R,5S)-5-Hydroxy-2-[(E,3S)-3-Hydroxyoct-1-Enyl]-3-Keto-Cyclopentyl]Hept-5-Enoic Acid; (5E,13E)-9,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oic Acid
• Molecular Formula: C₂₀H₃₂O₅
• Molecular Weight: 352.47
• CAS Registry Number: 41598-07-6
• SMILES: [C@H]1([C@H]([C@@H](O)CC1=O)C\C=C/CCCC(=O)O)\C=C\[C@@H](O)CCCCC
• InChI: 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
• InChIKey: BHMBVRSPMRCCGG-OUTUXVNYSA-N

Properties

• Density: 1.149g/cm³ (Cal.)
• Boiling point: 549.607°C at 760 mmHg (Cal.)
• Flash point: 300.254°C (Cal.)

References

• (1): Roberts L J, Sweetman B J . Metablic Fate of endogenously synthesized prostaglandin D2 in a human female with mastocytosis, Prostaglandins, 1985, 30, 383-400
• (2): Hayaishi O. Sleep-wake regulation by prostaglandins D2 and E2, J. Biol. Chem., 1988, 263, 14593-14596
• (3): Onoe H, Ueno R, Fujita I . Prostaglandin D2, a cerebral sleep-inducing substance in monkeys, Proc. Natl. Acad. Sci. USA, 1988, 85, 4082-4086
• (4): Giles H, Leff P. The biology and pharmacology of PGD2, Prostaglandins, 1988, 35, 277-300