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Nicotinamide ribonucleotide
[CAS# 1094-61-7]

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Identification
Classification Biochemical >> Enzymes and coenzymes
Name Nicotinamide ribonucleotide
Synonyms Nicotinamide mononucleotide; Nicotinamide ribonucleoside 5'-phosphate; Nicotinamide ribonucleotide; Nicotinamide ribotide; beta-D-NMN; beta-NMN
Molecular Structure CAS # 1094-61-7, Nicotinamide ribonucleotide, Nicotinamide mononucleotide, Nicotinamide ribonucleoside 5'-phosphate, Nicotinamide ribonucleotide, Nicotinamide ribotide, beta-D-NMN, beta-NMN
Molecular Formula C11H15N2O8P
Molecular Weight 334.22
CAS Registry Number 1094-61-7
EC Number 214-136-5
SMILES C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)N
Safety Data
Hazard Symbols symbol   GHS07 Warning    Details
Hazard Statements H315-H319-H335    Details
Precautionary Statements P261-P305+P351+P338    Details
SDS Available
up Discovory and Applicatios
Nicotinamide ribonucleotide (NMN) is a nucleotide derived from ribose and nicotinamide, a form of vitamin B3. The discovery of NMN dates back to early studies on the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme in cellular metabolism. Researchers identified NMN as an intermediate in the NAD+ biosynthesis pathway.

One of the most prominent applications of NMN is in the field of anti-aging research. NMN supplementation has been shown to increase NAD+ levels in cells, which decline with age. Higher NAD+ levels are associated with improved mitochondrial function, enhanced DNA repair, and better cellular health.

NMN plays a crucial role in regulating metabolic processes, making it a promising candidate for treating metabolic disorders. By boosting NAD+ levels, NMN enhances the function of enzymes involved in energy production and lipid metabolism. Research has shown that NMN supplementation can improve insulin sensitivity, reduce inflammation, and mitigate the effects of obesity and type 2 diabetes in animal models.

The neuroprotective properties of NMN have been explored in the context of neurodegenerative diseases such as Alzheimer's and Parkinson's. NAD+ is essential for neuronal survival and function, and its depletion is linked to neurodegeneration. NMN supplementation has been shown to protect neurons, enhance cognitive function, and reduce neuroinflammation in animal models.

Cardiovascular health is another area where NMN shows promise. NAD+ levels are critical for maintaining the function of the cardiovascular system, including the health of blood vessels and the heart. Research indicates that NMN can improve endothelial function, enhance blood flow, and reduce the risk of atherosclerosis.

NMN's ability to enhance mitochondrial function and energy production has also led to interest in its potential to improve athletic performance. By increasing NAD+ levels, NMN may boost endurance, reduce fatigue, and enhance recovery in athletes.
Market Analysis Reports
List of Reports Available for Nicotinamide ribonucleotide
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