LEE 011
[CAS# 1211441-98-3]

Identification

• Classification: Biochemical >> Inhibitor >> Cell cycle >> CDK inhibitor
• Name: LEE 011
• Synonyms: 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
• Molecular Formula: C₂₃H₃₀N₈O
• Molecular Weight: 434.54
• CAS Registry Number: 1211441-98-3
• EC Number: 807-111-0

Properties

• Solubility: Very slightly soluble (0.1 g/L) (25 ºC), Calc.^*
• Density: 1.39±0.1 g/cm³ (20 ºC 760 Torr), Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2014 ACD/Labs)

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411
Reproductive toxicity	Repr.	1B	H360FD
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Reproductive toxicity	Repr.	1B	H360