Auristatin E
[CAS# 160800-57-7]

Identification

• Name: Auristatin E
• Synonyms: N,N-Dimethyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide
• Molecular Formula: C₄₀H₆₉N₅O₇
• Molecular Weight: 732.01
• CAS Registry Number: 160800-57-7
• EC Number: 814-537-0

Properties

• Solubility: Very slightly soluble (0.95 g/L) (25 ºC), Calc.^*
• Density: 1.085±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 92-94 ºC^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2019 ACD/Labs)

^** Pettit, George R.; MX 9307574 A 2000.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Germ cell mutagenicity	Muta.	2	H341
Reproductive toxicity	Repr.	2	H361