Sodium hydrosulfide
[CAS# 16721-80-5]

Identification

• Classification: Inorganic chemical industry >> Inorganic salt >> Metal sulfides and sulfates
• Name: Sodium hydrosulfide
• Synonyms: Sodium bisulfide
• Molecular Formula: NaHS
• Molecular Weight: 56.06
• CAS Registry Number: 16721-80-5
• EC Number: 240-778-0
• SMILES: [Na+].[SH-]

Properties

• Melting point: 55 ºC
• Flash point: 90 ºC
• Water solubility: 620 g/L (20 ºC)

Safety Data

• Hazard Symbols: GHS02;GHS05;GHS06;GHS09 DangerGHS02;GHS05
• Hazard Statements: H226-H251-H290-H301-H314-H318-H400
• Precautionary Statements: P210-P233-P234-P235-P240-P241-P242-P243-P260-P264-P264+P265-P270-P273-P280-P301+P316-P301+P330+P331-P302+P361+P354-P303+P361+P353-P304+P340-P305+P354+P338-P316-P317-P321-P330-P363-P370+P378-P390-P391-P403+P235-P405-P406-P407-P410-P413-P420-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin corrosion	Skin Corr.	1B	H314
Acute toxicity	Acute Tox.	3	H301
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Serious eye damage	Eye Dam.	1	H318
Substances or mixtures corrosive to metals	Met. Corr.	1	H290
Flammable liquids	Flam. Liq.	3	H226
Self-heating substances or mixtures	Self-heat.	1	H251
Skin corrosion	Skin Corr.	1A	H314
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	3	H311
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411

• Transport Information: UN 2318;UN 1385;UN 2949

Discovory and Applicatios

Sodium hydrosulfide is an inorganic compound with the chemical formula NaHS. It is the sodium salt of the bisulfide anion and appears as a colorless to pale yellow crystalline solid with a characteristic odor of hydrogen sulfide (H₂S). Sodium hydrosulfide is highly soluble in water and forms a strongly alkaline solution. It is commonly encountered in its hydrated form, typically as NaHS·xH₂O, where the degree of hydration varies depending on the storage and processing conditions.

The compound has been known and utilized since the 19th century, with early references in chemical literature detailing its preparation through the direct absorption of hydrogen sulfide gas into sodium hydroxide solution. This reaction remains the standard method for producing sodium hydrosulfide on an industrial scale:
H₂S + NaOH → NaHS + H₂O

Sodium hydrosulfide is extensively used in various industrial applications. One of its primary uses is in the pulp and paper industry, particularly in the Kraft process for the production of wood pulp. In this process, NaHS acts as a source of sulfide ions, which help break down lignin, a complex polymer that binds cellulose fibers in wood. The effectiveness of sodium hydrosulfide in lignin degradation is critical to the efficient conversion of wood chips into pulp, which is then used to manufacture paper and paperboard products.

Another significant application of sodium hydrosulfide is in the mining industry, where it is employed as a flotation agent in the beneficiation of ores. In this context, it is particularly useful for the separation of copper, molybdenum, and other sulfide minerals. NaHS serves to depress certain unwanted minerals, making the desired metal components more amenable to selective flotation.

In the textile industry, sodium hydrosulfide is used as a reducing agent in the dyeing of synthetic and natural fibers. It is particularly effective in vat dyeing processes, where it helps convert dyes to their soluble leuco forms for application onto fabric. After dyeing, the oxidation of the leuco compound regenerates the original dye on the fiber.

The leather industry also utilizes sodium hydrosulfide for dehairing hides and skins during the tanning process. Its strong reducing properties and ability to break disulfide bonds in keratin make it effective in loosening hair from animal hides. This step is essential in the preparation of leather, enabling further treatment and finishing.

Sodium hydrosulfide has found use in chemical manufacturing as well. It is used in the synthesis of thiols, thioethers, and other sulfur-containing compounds. It serves as a convenient source of the hydrosulfide ion (HS⁻) in organic and inorganic reactions. Its reactivity with electrophiles allows the formation of a variety of sulfur-based functional groups, which are valuable intermediates in pharmaceutical and agrochemical synthesis.

Because of its ability to release hydrogen sulfide gas upon contact with acids or even moisture, sodium hydrosulfide must be handled with caution. Hydrogen sulfide is highly toxic and flammable, and exposure can be hazardous to human health. Therefore, NaHS is typically stored and transported in sealed containers under controlled conditions, and appropriate ventilation and protective equipment are required during handling.

Environmental considerations also play a role in the management of sodium hydrosulfide. Waste streams containing residual NaHS must be treated before discharge to prevent the release of hydrogen sulfide into the environment. Treatment methods often involve oxidation processes that convert sulfides to less harmful sulfate forms.

Sodium hydrosulfide continues to be a vital chemical in several major industries. Its unique chemical properties, including its solubility, reactivity, and reducing power, ensure its continued relevance in pulp processing, mineral extraction, dye manufacturing, and leather treatment. Its production and use are well-documented in industrial chemistry, and safety measures are established to mitigate its inherent risks.

References

2008. Sodium hydrosulfide alleviates pulmonary artery collagen remodeling in rats with high pulmonary blood flow. Heart and Vessels, 23(6).
DOI: 10.1007/s00380-008-1059-4

2012. Gastroprotective Effect of NaHS Against Mucosal Lesions Induced by Ischemia�Reperfusion Injury in Rat. Digestive Diseases and Sciences, 57(6).
DOI: 10.1007/s10620-012-2051-5

2020. Hydrogen sulfide acts downstream of jasmonic acid to inhibit stomatal development in Arabidopsis. Planta, 251(2).
DOI: 10.1007/s00425-019-03334-9