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Dihydrocapsaicin
[CAS# 19408-84-5]

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Complete supplier list of Dihydrocapsaicin
Identification
Classification Biochemical >> Chinese herbal medicine ingredients
Name Dihydrocapsaicin
Synonyms 8-Methyl-N-vanillylnonanamide
Molecular Structure CAS # 19408-84-5, Dihydrocapsaicin, 8-Methyl-N-vanillylnonanamide
Molecular Formula C18H29NO3
Molecular Weight 307.43
CAS Registry Number 19408-84-5
EC Number 606-308-7
SMILES CC(C)CCCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
Properties
Density 1.0±0.1 g/cm3, Calc.*Melting point|65.5-65.8 ºC
Index of Refraction 1.510, Calc.*
Boiling Point 497.4±35.0 ºC (760 mmHg), Calc.*
Flash Point 254.6±25.9 ºC, Calc.*
* Calculated using Advanced Chemistry Development (ACD/Labs) Software.
Safety Data
Hazard Symbols symbol symbol   GHS06;GHS07 Danger    Details
Hazard Statements H301-H315-H319-H335    Details
Precautionary Statements P261-P264-P264+P265-P270-P271-P273-P280-P301+P316-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P337+P317-P362+P364-P391-P403+P233-P405-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Skin irritationSkin Irrit.2H315
Eye irritationEye Irrit.2H319
Acute toxicityAcute Tox.3H301
Specific target organ toxicity - single exposureSTOT SE3H335
Specific target organ toxicity - single exposureSTOT SE3H336
Specific target organ toxicity - repeated exposureSTOT RE1H372
Acute toxicityAcute Tox.2H300
Skin sensitizationSkin Sens.1H317
Transport Information UN 3462
SDS Available
up Discovory and Applicatios
Dihydrocapsaicin is a pungent compound found in various Capsicum species, contributing significantly to the spiciness of chili peppers. It is a capsaicinoid, a group of compounds responsible for the heat associated with chili peppers. Dihydrocapsaicin was first isolated in the late 20th century during the extensive research on the chemical constituents of Capsicum species, which aimed to identify and characterize the compounds responsible for their unique flavor and pungency.

The synthesis of dihydrocapsaicin can be achieved through various methods, including extraction from natural sources and chemical synthesis. Natural extraction typically involves the isolation of capsaicinoids from chili peppers using organic solvents, followed by purification processes such as chromatography. Alternatively, synthetic approaches have been developed to create dihydrocapsaicin in the laboratory, providing researchers with a reliable source of the compound for further studies.

Dihydrocapsaicin has garnered significant interest for its various applications in food, pharmaceuticals, and cosmetics. In the food industry, it is primarily utilized as a flavoring agent and a natural preservative. Its ability to enhance flavor while providing a spicy kick makes it a popular ingredient in sauces, snacks, and seasoning blends. Additionally, dihydrocapsaicin is often used in spicy food products to provide consumers with a distinctive taste experience.

In the pharmaceutical industry, dihydrocapsaicin has been studied for its potential therapeutic properties. Research has indicated that it possesses analgesic and anti-inflammatory effects, making it a candidate for pain management formulations. Dihydrocapsaicin works by interacting with the transient receptor potential vanilloid 1 (TRPV1) channels, which are involved in pain sensation. This mechanism of action has led to the development of topical analgesic creams and patches containing dihydrocapsaicin to alleviate pain associated with conditions such as arthritis and neuropathic pain.

Furthermore, dihydrocapsaicin has been explored for its potential health benefits beyond pain relief. Studies have suggested that it may have antioxidant properties, contributing to its role in promoting overall health. The compound has also been investigated for its potential effects on metabolism and weight management. Some research indicates that dihydrocapsaicin may enhance metabolic rate and fat oxidation, making it a subject of interest in the field of weight loss and obesity management.

In the cosmetics industry, dihydrocapsaicin is being incorporated into products designed to improve skin health. Its anti-inflammatory and analgesic properties make it a suitable ingredient for formulations targeting skin irritations and conditions such as rosacea. Additionally, its ability to enhance blood circulation may contribute to the effectiveness of certain cosmetic products, promoting healthier-looking skin.

The versatility of dihydrocapsaicin has made it a valuable compound across various industries. As research continues, new applications and benefits are likely to be discovered, further expanding the potential uses of this fascinating capsaicinoid. Ongoing studies are also focused on understanding the optimal dosages and formulations that maximize the therapeutic effects of dihydrocapsaicin while minimizing any potential side effects.

In summary, dihydrocapsaicin is a significant capsaicinoid with a rich history of discovery and diverse applications in food, pharmaceuticals, and cosmetics. Its unique properties, coupled with its pungent flavor, make it a valuable ingredient in numerous products. As research advances, dihydrocapsaicin's potential benefits and applications will likely continue to evolve, solidifying its importance in various fields.
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