Dacomitinib Impurity 1
[CAS# 2190490-31-2]

Identification

• Name: Dacomitinib Impurity 1
• Synonyms: 1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one
• Molecular Formula: C₁₉H₁₆ClFN₄O₃
• Molecular Weight: 402.81
• CAS Registry Number: 2190490-31-2
• SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)N4C(CCC4=O)O

Properties

• Density: 1.5±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.709, Calc.^*
• Boiling Point: 662.5±55.0 ºC (760 mmHg), Calc.^*
• Flash Point: 354.5±31.5 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.