6-Chloro-4-(trifluoromethyl)-3-pyridinecarboxylic acid
[CAS# 261635-77-2]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyridine compound >> Pyridine derivative
• Name: 6-Chloro-4-(trifluoromethyl)-3-pyridinecarboxylic acid
• Synonyms: 6-Chloro-4-trifluoromethylnicotinic acid
• Molecular Formula: C₇H₃ClF₃NO₂
• Molecular Weight: 225.55
• CAS Registry Number: 261635-77-2
• EC Number: 672-886-2

Properties

• Solubility: Slightly soluble (3.6 g/L) (25 ºC), Calc.^*
• Density: 1.603±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 114-116 ºC (heptane )^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2017 ACD/Labs)

^** Cottet, Fabrice; Tetrahedron 2004, V60(51), P11869-11874.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	3	H301
Acute toxicity	Acute Tox.	4	H302
Acute toxicity	Acute Tox.	4	H332
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H312
Specific target organ toxicity - single exposure	STOT SE	3	H335
Eye irritation	Eye Irrit.	2	H319
Respiratory sensitization	Resp. Sens.	1	H334
Eye irritation	Eye Irrit.	2A	H319
Skin sensitization	Skin Sens.	1	H317