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5-Chloro-2-methyl-4-isothiazolin-3-one
[CAS# 26172-55-4]

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Complete supplier list of 5-Chloro-2-methyl-4-isothiazolin-3-one
Identification
Classification Chemical pesticide >> Fungicide >> Other fungicides
Name 5-Chloro-2-methyl-4-isothiazolin-3-one
Synonyms 5-Chloro-2-methyl-3(2H)-isothiazolone; 5-Chloro-2-methylisothiazolone; Kathon IXE
Molecular Structure CAS # 26172-55-4, 5-Chloro-2-methyl-4-isothiazolin-3-one, 5-Chloro-2-methyl-3(2H)-isothiazolone, 5-Chloro-2-methylisothiazolone, Kathon IXE
Molecular Formula C4H4ClNOS
Molecular Weight 149.59
CAS Registry Number 26172-55-4
EC Number 247-500-7
SMILES CN1C(=O)C=C(S1)Cl
Properties
Density 1.25 (14% aq.)
Melting point 52 ºC
Refractive index 1.378
Safety Data
Hazard Symbols symbol symbol symbol symbol   GHS05;GHS06;GHS07;GHS09 Danger    Details
Hazard Statements H300-H301+H311-H301-H310-H311-H314-H317-H318-H330-H331-H335-H400-H410    Details
Precautionary Statements P260-P261-P262-P264-P264+P265-P270-P271-P272-P273-P280-P284-P301+P316-P301+P330+P331-P302+P352-P302+P361+P354-P304+P340-P305+P354+P338-P316-P317-P319-P320-P321-P330-P333+P317-P361+P364-P362+P364-P363-P391-P403+P233-P405-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Acute hazardous to the aquatic environmentAquatic Acute1H400
Skin corrosionSkin Corr.1BH314
Skin sensitizationSkin Sens.1H317
Acute toxicityAcute Tox.3H301
Serious eye damageEye Dam.1H318
Acute toxicityAcute Tox.3H311
Chronic hazardous to the aquatic environmentAquatic Chronic1H410
Acute toxicityAcute Tox.2H330
Acute toxicityAcute Tox.2H310
Specific target organ toxicity - single exposureSTOT SE3H335
Acute toxicityAcute Tox.3H331
Acute toxicityAcute Tox.2H300
Skin sensitizationSkin Sens.1AH317
Skin corrosionSkin Corr.1CH314
Chronic hazardous to the aquatic environmentAquatic Chronic4H413
Flammable liquidsFlam. Liq.3H226
Specific target organ toxicity - single exposureSTOT SE1H370
Acute toxicityAcute Tox.4H302
Acute toxicityAcute Tox.4H312
Acute toxicityAcute Tox.4H332
Respiratory sensitizationResp. Sens.1H334
Skin sensitizationSkin Sens.1BH317
Chronic hazardous to the aquatic environmentAquatic Chronic3H412
Skin corrosionSkin Corr.1H314
Skin irritationSkin Irrit.2H315
Eye irritationEye Irrit.2H319
Acute toxicityAcute Tox.1H310
Acute toxicityAcute Tox.1H300
Eye irritationEye Irrit.2AH319
Acute toxicityAcute Tox.1H330
SDS Available
up Discovory and Applicatios
5-Chloro-2-methyl-4-isothiazolin-3-one, commonly abbreviated as CMIT, is a powerful biocide that was discovered in the mid-20th century during the development of industrial preservatives. CMIT belongs to the isothiazolinone family, which is known for its strong antimicrobial properties. The advent of this compound stems from the need for effective solutions to control microbial growth in various industrial and consumer products.

The molecular formula of CMIT is C4H4ClNOS. It has a chlorine-substituted isothiazolinone ring, which contributes to its biocidal activity. This structure enables CMIT to effectively disrupt the metabolic processes of microorganisms, making it a highly effective preservative. CMIT is often combined with other isothiazolinones, such as methylisothiazolinone (MIT), to enhance its antimicrobial efficacy.

One of the main applications of CMIT is as a preservative in industrial products. It is often used in paints, adhesives, and coatings to prevent microbial contamination, which can cause product deterioration and degradation. The presence of CMIT ensures the longevity and stability of these products by inhibiting the growth of bacteria, fungi, and algae.

CMIT is also used in personal care and cosmetic products such as shampoos, conditioners, and lotions. It acts as a preservative to prevent microbial growth, extending the shelf life of these products and ensuring they are safe for consumers. Due to its powerful biocidal properties, only low concentrations of CMIT are required for effective preservation.

In water treatment applications, CMIT is used to control microbial growth in cooling towers, pulp and paper mills, and petroleum extraction systems. Its ability to eliminate a wide range of microorganisms makes it valuable in maintaining water quality and preventing biofouling, which can lead to operational inefficiencies and equipment damage.

CMIT is found in a variety of household cleaning products and disinfectants. It helps ensure that these products effectively eliminate bacteria and other pathogens on surfaces, creating a hygienic environment. Including CMIT in these formulations enhances their antimicrobial properties, making them more effective at maintaining cleanliness.

In the paint and coatings industry, CMIT is added to formulations to prevent microbial contamination during storage and application. This use helps maintain product quality and prevent deterioration that can result in financial losses and compromised performance. CMIT ensures that paints and coatings remain effective and beautiful for a long time.

Although CMIT is highly effective as a biocide, its use is regulated due to the potential health risks associated with exposure. Regulatory agencies, such as the Environmental Protection Agency (EPA) and the European Chemicals Agency (ECHA), have established safe concentration guidelines for CMIT in various applications to minimize adverse effects on human health and the environment.
Market Analysis Reports
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