4-Hydroxyquinoline-3-carboxylic acid ethyl ester
[CAS# 26892-90-0]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Quinoline compound
• Name: 4-Hydroxyquinoline-3-carboxylic acid ethyl ester
• Synonyms: Ethyl 4-hydroxyquinoline-3-carboxylate; NSC 4345
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.22
• CAS Registry Number: 26892-90-0
• EC Number: 803-448-2

Properties

• Solubility: Very slightly soluble (0.54 g/L) (25 ºC), Calc.^*
• Density: 1.280±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 275-276 ºC^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2016 ACD/Labs)

^** Schofield, K.; Journal of the Chemical Society 1946, P1033-5.

Safety Data

• Hazard Symbols: Xi
• Risk Codes: R36
• Safety Description: S26

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Eye irritation	Eye Irrit.	2A	H319
Specific target organ toxicity - single exposure	STOT SE	3	H335