CFTR(inh)-172
[CAS# 307510-92-5]

Identification

• Classification: Biochemical >> Inhibitor >> Transmembrane transporters >> CFTR inhibitor
• Name: CFTR(inh)-172
• Synonyms: 3-[(3-Trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone; CFTR(inh)-172; Cystic fibrosis transmembrane conductance regulator inhibitor CFTR(inh)-172
• Molecular Formula: C₁₈H₁₀F₃NO₃S₂
• Molecular Weight: 409.40
• CAS Registry Number: 307510-92-5
• EC Number: 636-554-0

Properties

• Solubility: Insoluble (8.6E^-4 g/L) (25 ºC), Calc.^*
• Density: 1.61±0.1 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 182-183 ºC^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2017 ACD/Labs)

^** Sonawane, N. D.; Bioorganic & Medicinal Chemistry 2008, V16(17), P8187-8195.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute hazardous to the aquatic environment	Aquatic Acute	1	H400
Eye irritation	Eye Irrit.	2	H319
Chronic hazardous to the aquatic environment	Aquatic Chronic	1	H410
Skin sensitization	Skin Sens.	1	H317
Skin irritation	Skin Irrit.	2	H315