Disodium Bathocuproinedisulfonate
[CAS# 52698-84-7]

Identification

• Name: Disodium Bathocuproinedisulfonate
• Synonyms: Sodium 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline-3,8-disulfonate
• Molecular Formula: C₂₆H₁₈N₂Na₂O₆S₂
• Molecular Weight: 564.54
• CAS Registry Number: 52698-84-7
• EC Number: 258-111-7
• SMILES: CC1=C(C(=C2C=CC3=C(C(=C(N=C3C2=N1)C)S(=O)(=O)[O-])C4=CC=CC=C4)C5=CC=CC=C5)S(=O)(=O)[O-].[Na+].[Na+]

Properties

• Solubility: 50 mg/mL (water)

Discovory and Applicatios

Bathocuproin disulphonate disodium salt (BCS) is a compound with significant applications in analytical chemistry, especially biochemistry. Known for its ability to form stable complexes with copper ions, BCS has become a valuable tool for researchers and scientists in various fields.

The discovery of BCS can be traced back to the early studies of complexing agents and their applications in metal ion detection. The parent compound, bathocuproin, was originally synthesized to explore its ability to form chelates with metal ions. Sulfonation of bathocuproin to give BCS improves its solubility in water, making it more suitable for a wider range of applications.

BCS is known for its high specificity and sensitivity for copper (I) ions. It works by forming a strong and stable complex with copper (I) that is intensely colored. This color change provides a visual and measurable method to detect and quantify copper ions in solution. The unique orange-red color of the BCS-copper (I) complex makes it easily detectable by spectrophotometry.

One of the main advantages of BCS is its selectivity for copper (I) ions over copper (II) ions and other metal ions. This selectivity is critical in biochemical applications that require the precise detection and measurement of copper(I) without interference from other metal ions.

BCS is widely used in biochemical assays to determine copper levels in biological samples. Its ability to form stable complexes with copper(I) allows for accurate measurement of copper concentrations in cells, tissues, and body fluids. This is particularly important in studies related to copper metabolism and its role in various physiological and pathological processes.

In environmental monitoring, BCS is used to detect and measure copper contamination in water sources. Its high sensitivity and selectivity make it an excellent tool for assessing the impact of copper contamination on ecosystems. By accurately measuring copper levels, researchers can evaluate the effectiveness of pollution control measures and ensure compliance with environmental regulations.

In pharmaceutical research, BCS is used to study the interactions between copper and potential drug candidates. Understanding how drugs interact with copper ions can provide insight into their mechanisms of action and potential side effects. BCS helps characterize these interactions and optimize the development of copper-based therapeutics.