Online Database of Chemicals from Around the World

Glycine
[CAS# 56-40-6]

Top Active Suppliers
Hangzhou Verychem Science And Technology Co., Ltd. China Inquire  
+86 (571) 8816-2785
+86 13606544505
lucy@verychem.com
Chemical manufacturer since 2004
chemBlink massive supplier since 2021
Qingdao Free Trade Zone United International Co., Ltd. China Inquire  
+86 (532) 83893696
+86 13808950921
jason.wang@unitedint.com
QQ chat
Chemical distributor
chemBlink standard supplier since 2006
CAC Shanghai (Group) Co., Ltd. China Inquire  
+86 (21) 6239-8696
service@cacch.com
Chemical distributor since 1992
chemBlink standard supplier since 2006
Shijiazhuang Shixing Amino Acid Co., Ltd. China Inquire  
+86 (311) 8604-6166
aacid@126.com
Chemical manufacturer
chemBlink standard supplier since 2007
Nanjing Search Biotech Co., Ltd. China Inquire  
+86 (25) 8168-2922
8586-0978
+86 18913919581
trade@searchbio.com.cn
sales@searchbio.com.cn
Linda@searchbio.com.cn
QQ chat
Chemical manufacturer since 2007
chemBlink standard supplier since 2007
Shanghai Jinhuan Chemical Co., Ltd. China Inquire  
+86 (21) 6142-0008
chenhui79820@hotmail.com
Chemical manufacturer since 2007
chemBlink standard supplier since 2008
Baoji Herbest Bio-tech Co., Ltd. China Inquire  
+86 (917) 888-1635
root@herbest.cn
QQ chat
Chemical manufacturer since 2008
chemBlink standard supplier since 2008
Simagchem Corporation China Inquire  
+86 13806087780
sale@simagchem.com
Chemical manufacturer since 2002
chemBlink standard supplier since 2008
Complete supplier list of Glycine
Identification
Classification Biochemical >> Common amino acids and protein drugs
Name Glycine
Synonyms Aminoacetic acid; Gly; Iconyl; Monazol
Molecular Structure CAS # 56-40-6, Glycine, Aminoacetic acid, Gly, Iconyl, Monazol
Protein Sequence G
Molecular Formula C2H5NO2
Molecular Weight 75.07
CAS Registry Number 56-40-6
EC Number 200-272-2
SMILES C(C(=O)O)N
Properties
Density 1.595
Melting point 182 ºC
Boiling point 233 ºC
Water solubility 25 g/100 mL (25 ºC)
Safety Data
Hazard Symbols symbol   GHS07 Warning    Details
Safety Description S22;S24/25    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Eye irritationEye Irrit.2H319
Skin irritationSkin Irrit.2H315
Specific target organ toxicity - single exposureSTOT SE3H335
SDS Available
up Discovory and Applicatios
Glycine is the simplest of the 20 amino acids commonly found in proteins. It plays a vital role in various biological processes and has a wide range of applications in medicine, industry, and research.

Glycine was first discovered in 1820 by French chemist Henri Braconnot while studying gelatin. Braconnot hydrolyzed gelatin with sulfuric acid and isolated glycine, a sweet crystalline substance. This discovery was an important milestone in understanding the composition of proteins and the role of amino acids in biological systems.

Glycine has a molecular formula of C2H5NO2 and is characterized by a simple structure: there is only one hydrogen atom in the side chain. This makes glycine unique among amino acids as it is the only one that is achiral. Glycine is extremely soluble in water and has an isoelectric point of about 6.06.

Glycine performs a variety of essential functions in the body. It is a building block of proteins and is incorporated into peptides and proteins during translation. Glycine acts as an inhibitory neurotransmitter in the central nervous system, especially in the spinal cord, brainstem, and retina. It is the main component of collagen, the most abundant protein in the human body, which provides structural support for tissues. Glycine is involved in the synthesis of various biomolecules, including heme, purines, and creatine.

Glycine is used in a variety of medical applications. It is used as a dietary supplement to support muscle growth, improve sleep quality, and promote overall health. Glycine is a component of certain intravenous (IV) solutions and oral rehydration salts. It is also used as a buffering agent in antacids.

Industrially, glycine has a variety of uses. Glycine is used as a flavor enhancer and a component of artificial sweeteners. Its sweet taste and ability to mask bitterness make it valuable in food processing. It is used in the production of herbicides, such as glyphosate, which is one of the most widely used herbicides worldwide.

Glycine is widely used in biochemical research and laboratory applications. It is used in buffer solutions for electrophoresis and other biochemical techniques due to its buffering capacity in the physiological pH range. Glycine is a component of many cell culture media, supporting the growth and maintenance of cells in vitro.

Glycine is also used in the cosmetic industry and is included in formulations for its moisturizing and conditioning properties. Glycine helps improve skin elasticity and smoothness.

Glycine is generally recognized as safe (GRAS) by regulatory agencies. It is well tolerated and has low toxicity, making it suitable for use in a variety of applications, including food and pharmaceuticals. Glycine’s applications range from medical and industrial uses to research and cosmetics, highlighting its versatility. Its fundamental role in biological processes and its functional properties make it a valuable substance in multiple fields. As a naturally occurring amino acid, glycine is biocompatible and can be easily utilized or metabolized by the human body. This makes it an ideal candidate for use in the medical and therapeutic fields.

References

2025. Effects of environmentally relevant concentrations of glyphosate and aminomethylphosphonic acid on biotransformation and stress response proteins in the liver of zebrafish (Danio rerio). Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 49.
DOI: 10.1016/j.cbd.2024.101366

2025. Determination of α-methylenecyclopropylglycine in Shahi and China litchi cultivars at three different maturity stages: A quantitative study using liquid chromatography tandem mass spectrometry. Food Chemistry, 466.
DOI: 10.1016/j.foodchem.2024.140971

1857. Zur Chemie der Nebennieren. Archiv für pathologische Anatomie und Physiologie und für klinische Medicin, 13(3-4).
DOI: 10.1007/bf01939540
Market Analysis Reports
List of Reports Available for Glycine
Related Products
Glycidyl 4-nonylphenyl ether  (R)-(-)-Glycidyl nosylate  (S)-(+)-Glycidyl nosylate  12-(Glycidyloxy)oleic acid glycerol ester  (3-Glycidyloxypropyl)triethoxysilane  Glycidyl phenyl ether  (2S)-(+)-Glycidyl tosylate  (2R)-(-)-Glycidyl tosylate  Glycinamide  Glycinamide hydrochloride  [15N]Glycine  Glycine Cresol Red  Glycine ethyl ester hydrochloride  Glycine hydrochloride  Glycine isopropyl ester hydrochloride  Glycine lauryl ester hydrochloride  Glycine methyl ester hydrochloride  Glycerol tristearate  D-glycero-D-manno-Heptonic acid 2-phenylhydrazide  Glycerophosphoric acid