Sodium persulfate
[CAS# 7775-27-1]

Identification

• Classification: Inorganic chemical industry >> Inorganic salt >> Metal sulfides and sulfates
• Name: Sodium persulfate
• Synonyms: Sodium peroxydisulfate
• Molecular Formula: Na₂S₂O₈
• Molecular Weight: 238.09
• CAS Registry Number: 7775-27-1
• EC Number: 231-892-1
• SMILES: [O-]S(=O)(=O)OOS(=O)(=O)[O-].[Na+].[Na+]

Properties

• Density: 2.4 g/mL (Expl.)
• Melting point: 100 ºC (Expl.)
• Solubility: water: 550 g/L (20 ºC) (Expl.)

Safety Data

• Hazard Symbols: GHS03;GHS07;GHS08 Danger
• Hazard Statements: H272-H302-H315-H317-H319-H334-H335
• Precautionary Statements: P210-P220-P233-P260-P261-P264-P264+P265-P270-P271-P272-P280-P284-P301+P317-P302+P352-P304+P340-P305+P351+P338-P319-P321-P330-P332+P317-P333+P317-P337+P317-P342+P316-P362+P364-P370+P378-P403-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Skin sensitization	Skin Sens.	1	H317
Respiratory sensitization	Resp. Sens.	1	H334
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315
Eye irritation	Eye Irrit.	2	H319
Oxidising solids	Ox. Sol.	3	H272
Oxidising liquids	Ox. Liq.	3	H272
Oxidising solids	Ox. Sol.	2	H272
Skin sensitization	Skin Sens.	1A	H317
Acute toxicity	Acute Tox.	4	H332
Oxidising solids	Ox. Sol.	1	H271
Serious eye damage	Eye Dam.	1	H318
Oxidising liquids	Ox. Liq.	2	H272
Serious eye damage	Eye Dam.	1	H319
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412

• Transport Information: UN 1505

Discovory and Applicatios

Sodium persulfate (Na₂S₂O₈), also known as sodium peroxydisulfate, is a white crystalline inorganic salt widely recognized for its strong oxidizing properties. It was identified as part of the family of persulfate salts that have been studied since the late 19^th century. Industrial production of sodium persulfate primarily involves the electrolytic oxidation of sodium hydrogen sulfate or sodium sulfate solutions in sulfuric acid. This electrochemical process occurs at an anode—traditionally platinum, and more recently boron-doped diamond electrodes have been employed—which facilitates the formation of the persulfate ion (S₂O₈²⁻) by coupling two sulfate radicals generated at the electrode surface.

The electrolytic synthesis is carefully controlled with respect to current density, temperature, and electrolyte concentration to optimize yield and minimize side reactions such as oxygen evolution, which decrease efficiency. Typically, the concentration of sodium persulfate in solution is kept below its solubility limit of approximately 0.6 mol/L at ambient temperature to avoid precipitation. Under optimized industrial conditions, current efficiencies of around 60% can be achieved at moderate temperatures near 22 °C. Boron-doped diamond electrodes have improved stability and selectivity, allowing more efficient persulfate generation through distinct mechanisms including direct oxidation of sulfate ions and indirect formation via hydroxyl radicals.

Sodium persulfate is extensively used as a radical initiator in polymer chemistry. Upon thermal decomposition or dissolution in water, it produces sulfate radicals (SO₄^•−) that initiate free radical polymerization of monomers such as styrene and acrylates. This property makes it essential in producing polymers like styrene-butadiene rubber and acrylonitrile-butadiene-styrene (ABS) copolymers. The controlled radical generation by sodium persulfate enables precise regulation of polymer molecular weights and architectures, important in manufacturing adhesives, coatings, and water treatment polymers.

Besides polymerization, sodium persulfate is used in organic synthesis as an oxidizing agent. It facilitates reactions such as Elbs persulfate oxidation and Boyland–Sims oxidation and participates in radical-mediated transformations, including the synthesis of bioactive molecules. Its ability to generate sulfate radicals under mild conditions broadens its applicability in chemical modification processes.

In the electronics industry, sodium persulfate serves as a copper etchant in the fabrication of printed circuit boards. Its oxidizing capability allows it to dissolve unwanted copper efficiently without excessively attacking the substrate. Additionally, it finds use in soil and groundwater remediation, where activated persulfate systems produce sulfate radicals capable of degrading persistent organic pollutants. Textile industries employ sodium persulfate for oxidative desizing and modification of starches, and it is also a component in hair bleaching and detergent formulations.

Handling sodium persulfate requires safety precautions due to its strong oxidizing nature, which can cause irritation to skin, eyes, and respiratory tract. It should be stored away from combustible materials and moisture to maintain stability. Its combination of effective radical generation, ease of handling, and broad application spectrum has established sodium persulfate as a valuable chemical in industrial and environmental technologies.

References

2020. Oxidation of nine petroleum hydrocarbon compounds by combined hydrogen peroxide/sodium persulfate catalyzed by siderite. Environmental Science and Pollution Research, 27(29).
DOI: 10.1007/s11356-020-08968-x

2017. Degradation of propyl paraben by activated persulfate using iron-containing magnetic carbon xerogels: investigation of water matrix and process synergy effects. Environmental Science and Pollution Research, 25(11).
DOI: 10.1007/s11356-017-0178-9

2017. A comparatively optimization of dosages of oxidation agents based on volatile solids and dry solids content in dewatering of sewage sludge. Water Research, 126.
DOI: 10.1016/j.watres.2017.09.044