Colchiceine
[CAS# 477-27-0]

Identification

• Name: Colchiceine
• Synonyms: N-[(7S)-10-Hydroxy-9-Keto-1,2,3-Trimethoxy-6,7-Dihydro-5H-Benzo[D]Heptalen-7-Yl]Acetamide; N-[(7S)-10-Hydroxy-1,2,3-Trimethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[D]Heptalen-7-Yl]Ethanamide; Kbiogr_001044
• Molecular Formula: C₂₁H₂₃NO₆
• Molecular Weight: 385.42
• CAS Registry Number: 477-27-0
• EINECS: 207-512-5
• SMILES: [C@H]3(C1=CC(C(=CC=C1C2=C(C=C(C(=C2OC)OC)OC)CC3)O)=O)NC(=O)C
• InChI: 1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(26-2)20(27-3)21(28-4)19(12)13-6-8-16(24)17(25)10-14(13)15/h6,8-10,15H,5,7H2,1-4H3,(H,22,23)(H,24,25)/t15-/m0/s1
• InChIKey: PRGILOMAMBLWNG-HNNXBMFYSA-N

Properties

• Density: 1.3±0.1g/cm³ (Cal.)
• Boiling point: 731.5±60.0°C at 760 mmHg (Cal.)
• Flash point: 396.2±32.9°C (Cal.)

References

• (1): Marino Cavazza and Francesco Pietra. Tautomeric selectivity towards colchicinoids in the tosylation of colchiceine on a heterogeneous, easily removable catalyst, Org. Biomol. Chem., 2003, 1, 3002.