5-Amino-6-Chloro-N-[(1-Isobutyl-4-Piperidinyl)Methyl]-2-Methylimidazo[1,2-a]Pyridine-8-Carboxamide
[CAS# 519148-48-2]

Identification

• Name: 5-Amino-6-Chloro-N-[(1-Isobutyl-4-Piperidinyl)Methyl]-2-Methylimidazo[1,2-a]Pyridine-8-Carboxamide
• Synonyms: 5-Amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)-4-piperidinyl]methyl]-imidazo[1,2-a]pyridine-8-carboxamide; CJ 033466
• Molecular Formula: C₁₉H₂₈ClN₅O
• Molecular Weight: 377.91
• CAS Registry Number: 519148-48-2
• SMILES: CC1=CN2C(=C(C=C(C2=N1)C(=O)NCC3CCN(CC3)CC(C)C)Cl)N
• InChI: 1S/C19H28ClN5O/c1-12(2)10-24-6-4-14(5-7-24)9-22-19(26)15-8-16(20)17(21)25-11-13(3)23-18(15)25/h8,11-12,14H,4-7,9-10,21H2,1-3H3,(H,22,26)
• InChIKey: ISKHMDNIWXPUGR-UHFFFAOYSA-N

Properties

• Density: 1.3±0.1g/cm³ (Cal.)
• Refractive index: 1.646 (Cal.)
• solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol

References

• (1): Mikami T., Ochi Y., Suzuki K., Saito T., Sugie Y., Sakakibara M.. 5-Amino-6-chloro-N-[(1-isobutylpiperidin-4-yl)methyl]-2-methylimidazo[1,2- ]pyridine-8-carboxamide (CJ-033,466), a Novel and Selective 5-Hydroxytryptamine4 Receptor Partial Agonist: Pharmacological Profile in Vitro and Gastroprokinetic Effect in Conscious Dogs, Journal of Pharmacology and Experimental Therapeutics, 2008