Sodium metaphosphate
[CAS# 10124-56-8]

Identification

• Classification: Inorganic chemical industry >> Inorganic salt >> Phosphides, metal phosphoric acid, metaphosphoric acid, hypophosphorous acid and pyrophosphate
• Name: Sodium metaphosphate
• Synonyms: Sodium hexametaphosphate; Metaphosphoric acid hexasodium salt
• Molecular Formula: Na₆P₆O₁₈
• Molecular Weight: 611.77
• CAS Registry Number: 10124-56-8
• EC Number: 233-343-1
• SMILES: [O-]P1(=O)OP(=O)(OP(=O)(OP(=O)(OP(=O)(OP(=O)(O1)[O-])[O-])[O-])[O-])[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

Properties

• Density: 2.181 g/mL (Expl.)
• Melting point: 628 ºC (Expl.)
• Boiling point: 1500 ºC (Expl.)
• Refraction index: 1.482 (Expl.)

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H315-H319-H335
• Precautionary Statements: P261-P280-P305+351+338-P304+P340-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335
Serious eye damage	Eye Dam.	1	H318
Skin corrosion	Skin Corr.	1C	H314
Eye irritation	Eye Irrit.	2	H320
Skin mild irritation	Skin Mild Irrit. 99	3	H316

Discovory and Applicatios

Sodium metaphosphate is a sodium salt of metaphosphoric acid commonly represented by the empirical formula (NaPO₃)_n, where n denotes the degree of polymerization. It belongs to the broader class of condensed phosphates formed by the dehydration of orthophosphates at elevated temperatures. The compound is typically obtained as a white, glassy or crystalline solid that is highly soluble in water, forming solutions that contain polymeric phosphate species. Its development and characterization are closely connected to the systematic study of phosphate chemistry in the 19th and early 20th centuries.

The distinction between orthophosphates, pyrophosphates, and metaphosphates emerged from classical investigations of phosphoric acid derivatives. Chemists established that heating sodium dihydrogen phosphate or related salts leads to stepwise dehydration and condensation reactions, producing chains or cyclic structures composed of repeating PO₃ units. These condensed phosphates were collectively referred to as metaphosphates. Advances in analytical chemistry, including titration methods and later spectroscopic techniques such as infrared spectroscopy and nuclear magnetic resonance, clarified that sodium metaphosphate may exist in various structural forms, ranging from cyclic trimers to long-chain linear polymers.

One historically important commercial form of sodium metaphosphate is the glassy, high-molecular-weight material produced by controlled thermal processing of sodium phosphate salts. This material became widely known in the early 20th century after industrial-scale production methods were established. Detailed structural studies demonstrated that its backbone consists of repeating phosphate tetrahedra linked by shared oxygen atoms, forming linear polyphosphate chains. The sodium ions balance the negative charges along the polymeric framework and influence properties such as solubility and viscosity.

The industrial development of sodium metaphosphate was driven by its distinctive physicochemical properties. In aqueous solution, it can act as a sequestrant by binding polyvalent metal cations such as calcium and magnesium. This ability to form soluble complexes with hardness ions led to its adoption in water treatment and detergent formulations. By sequestering calcium ions, sodium metaphosphate prevents precipitation of insoluble salts and enhances cleaning efficiency. Extensive practical evaluations confirmed its effectiveness in softening water and stabilizing formulations containing metal-sensitive components.

In the food industry, sodium metaphosphate has been employed as a stabilizing and texturizing agent. Its capacity to interact with proteins and to modify ionic strength has been used to influence the water-holding properties of processed foods. Regulatory assessments and compositional analyses have documented its functional roles in certain applications, where it contributes to consistency and product stability. These uses are grounded in established knowledge of polyphosphate chemistry and its interaction with biological macromolecules.

Sodium metaphosphate has also been utilized in ceramics and materials processing. In ceramic slip formulations, it serves as a deflocculant, dispersing fine particles and reducing viscosity at a given solids content. This effect arises from adsorption of polyphosphate chains onto particle surfaces, increasing electrostatic repulsion and improving suspension stability. Empirical studies in ceramic engineering have demonstrated that small additions can significantly alter rheological behavior, enabling more efficient shaping and casting processes.

In addition, sodium metaphosphate has found application in corrosion control and scale inhibition in certain industrial water systems. By complexing metal ions and influencing crystal growth, it can reduce deposition of scale-forming minerals. Investigations of its performance under various temperature and pH conditions have characterized its hydrolytic stability and gradual conversion to shorter-chain phosphates over time in aqueous environments.

Chemically, sodium metaphosphate undergoes hydrolysis in water, particularly under acidic or basic conditions, reverting progressively to orthophosphate species. This behavior has been quantified through kinetic studies and informs both its practical use and storage considerations. Thermal analysis has further characterized its phase transitions and glass-forming tendencies.

From its origins in foundational phosphate research to its established roles in detergents, food processing, ceramics, and water treatment, sodium metaphosphate represents a significant example of applied inorganic polymer chemistry. Its structure, reactivity, and complexation properties have been extensively investigated, providing a solid scientific basis for its continued industrial and technological use.

References

2025. Histological and radiographic assessment of the regenerative potential of sodium hexametaphosphate (SHMP) as a novel direct pulp capping material in an animal model. BMC Oral Health.
DOI: 10.1186/s12903-024-05297-0

2024. Multispectroscopic and computational insights into amyloid fibril formation of alpha lactalbumin induced by sodium hexametaphosphate. Scientific Reports.
DOI: 10.1038/s41598-024-80897-y