Defactinib
[CAS# 1073154-85-4]

Identification

• Classification: Biochemical >> Inhibitor >> Angiogenesis >> FAK inhibitor
• Name: Defactinib
• Synonyms: N-Methyl-4-[[4-[[[3-[methyl(methylsulfonyl)amino]-2-pyrazinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]benzamide; VS 6063
• Molecular Formula: C₂₀H₂₁F₃N₈O₃S
• Molecular Weight: 510.49
• CAS Registry Number: 1073154-85-4
• EC Number: 969-109-7

Properties

• Solubility: Very slightly soluble (0.21 g/L) (25 ºC), Calc.^*
• Density: 1.495±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2015 ACD/Labs)

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H302
Specific target organ toxicity - single exposure	STOT SE	3	H335