(Cyclopropylmethyl)hydrazine hydrochloride
[CAS# 1181457-83-9]

Identification

• Classification: Chemical reagent >> Organic reagent >> Hydrazine
• Name: (Cyclopropylmethyl)hydrazine hydrochloride
• Molecular Formula: C₄H₁₁ClN₂
• Molecular Weight: 122.60
• CAS Registry Number: 1181457-83-9
• EC Number: 855-185-8
• SMILES: C1CC1CNN.Cl

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H312-H315-H319-H332-H335
• Precautionary Statements: P261-P264-P264+P265-P270-P271-P280-P301+P317-P302+P352-P304+P340-P305+P351+P338-P317-P319-P321-P330-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2A	H319
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H312
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H302

Discovory and Applicatios

(Cyclopropylmethyl)hydrazine hydrochloride is an organic compound that has garnered interest in medicinal chemistry and pharmaceutical research. It is a hydrazine derivative characterized by a cyclopropylmethyl group attached to the hydrazine moiety. This compound has emerged as a subject of study due to its potential applications in various therapeutic areas, including anti-cancer and neuroprotective research.

The discovery of (cyclopropylmethyl)hydrazine hydrochloride can be traced back to the broader investigation of hydrazine derivatives, which have been explored for their biological activities since the mid-20th century. Researchers have synthesized various hydrazine compounds, seeking to exploit their unique structural features and reactivity. The specific interest in (cyclopropylmethyl)hydrazine arose from studies investigating the structure-activity relationships of hydrazine-based compounds, which have demonstrated a range of pharmacological effects.

One of the most notable applications of (cyclopropylmethyl)hydrazine hydrochloride is its potential as an anti-cancer agent. Research has indicated that certain hydrazine derivatives possess cytotoxic properties, which can inhibit the growth of cancer cells. Initial studies have demonstrated that (cyclopropylmethyl)hydrazine hydrochloride may exert its anti-cancer effects through mechanisms such as inducing apoptosis and inhibiting cell proliferation. These properties have made it a candidate for further investigation in the development of novel anti-cancer therapies.

Additionally, (cyclopropylmethyl)hydrazine hydrochloride has been studied for its neuroprotective effects. Preliminary research has suggested that hydrazine derivatives may help mitigate neurodegenerative processes, potentially offering protective benefits against conditions such as Alzheimer’s disease and Parkinson’s disease. The ability of this compound to cross the blood-brain barrier and its interactions with various neurochemical pathways have fueled interest in its therapeutic potential in neurology.

The synthesis of (cyclopropylmethyl)hydrazine hydrochloride typically involves the reaction of cyclopropylmethylamine with hydrazine derivatives under controlled conditions, followed by hydrochloric acid treatment to form the hydrochloride salt. This method allows for the efficient production of the compound, facilitating its use in research and development.

Despite its promising applications, further research is needed to fully elucidate the mechanisms of action, pharmacokinetics, and safety profile of (cyclopropylmethyl)hydrazine hydrochloride. Understanding these factors is crucial for advancing its potential therapeutic uses and developing appropriate dosing regimens. As with many hydrazine derivatives, there are safety concerns regarding toxicity and carcinogenicity, necessitating careful evaluation in preclinical and clinical studies.

In summary, (cyclopropylmethyl)hydrazine hydrochloride is a compound of interest in medicinal chemistry, particularly for its potential anti-cancer and neuroprotective properties. The ongoing exploration of its pharmacological effects underscores the importance of hydrazine derivatives in drug development. As research progresses, (cyclopropylmethyl)hydrazine hydrochloride may contribute to advancements in therapeutic strategies for various diseases.