2-(2-Aminoethoxy)-1,1-dimethoxyethane
[CAS# 1228258-40-9]

Identification

• Classification: Organic raw materials >> Ether compounds and their derivatives
• Name: 2-(2-Aminoethoxy)-1,1-dimethoxyethane
• Molecular Formula: C₆H₁₅NO₃
• Molecular Weight: 149.19
• CAS Registry Number: 1228258-40-9
• EC Number: 871-712-4
• SMILES: COC(COCCN)OC

Properties

• Density: 1.0±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.425, Calc.^*
• Boiling Point: 196.9±25.0 ºC (760 mmHg), Calc.^*
• Flash Point: 69.9±16.8 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS05;GHS07 Danger
• Hazard Statements: H227-H314
• Precautionary Statements: P280-P305+P351+P338-P310

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Specific target organ toxicity - single exposure	STOT SE	3	H335
Skin corrosion	Skin Corr.	1	H314
Skin corrosion	Skin Corr.	1B	H314

Discovory and Applicatios

2-(2-Aminoethoxy)-1,1-dimethoxyethane is an organic compound that has attracted interest due to its chemical structure and potential applications in various fields, including medicinal chemistry and material science. This substance features an aminoethoxy group attached to an ethane backbone, along with two methoxy groups on the same molecule. The presence of both an amino group and methoxy functionalities provides the compound with a unique set of properties that make it suitable for use in a range of chemical reactions and formulations.

The discovery of 2-(2-aminoethoxy)-1,1-dimethoxyethane can be traced back to the growing interest in functionalized ether derivatives, which are known for their versatility in synthetic chemistry. Compounds with aminoethoxy and methoxy groups are particularly valuable because they can participate in a variety of reactions, including nucleophilic substitutions and condensation reactions. The first detailed studies on this compound were conducted as part of a broader effort to explore the reactivity and applications of amines and ethers in organic synthesis. Research into 2-(2-aminoethoxy)-1,1-dimethoxyethane continues, focusing on its use as a building block for more complex molecules with diverse biological and chemical properties.

The synthesis of 2-(2-aminoethoxy)-1,1-dimethoxyethane typically involves the reaction of appropriate starting materials, such as ethylene glycol derivatives and amines, under controlled conditions. One of the most common synthetic routes involves the use of ethylene oxide or other reactive ethyl groups, followed by nucleophilic substitution with an amine. This method allows for efficient incorporation of the aminoethoxy group into the structure, which is critical for the compound's reactivity in subsequent chemical processes. The introduction of the methoxy groups is typically achieved by methoxylation reactions, which add additional functional groups to the molecule and enhance its stability and solubility in various solvents.

2-(2-Aminoethoxy)-1,1-dimethoxyethane has shown promise in a variety of applications. One of its most significant uses is in the development of new pharmaceutical compounds. Due to its amino and ether functionalities, this compound can act as a precursor for the synthesis of more complex molecules with potential therapeutic effects. It is also being explored for its role in creating novel ligands for metal ions in coordination chemistry, as well as in the development of functionalized polymers and other materials. The ability to modify the structure of 2-(2-aminoethoxy)-1,1-dimethoxyethane by introducing additional functional groups opens up possibilities for the creation of specialized molecules with enhanced properties for drug delivery, catalysis, and material science.

In conclusion, 2-(2-aminoethoxy)-1,1-dimethoxyethane is a versatile compound with significant potential in both chemical synthesis and pharmaceutical development. Its unique structure, which incorporates both amino and methoxy groups, allows it to participate in a variety of chemical reactions and makes it useful as a building block for more complex molecules. Ongoing research into the compound's applications continues to explore its potential in a wide range of fields.