N-(2-Bromo-5-methoxyphenyl)acetamide
[CAS# 123027-99-6]

Identification

• Classification: Organic raw materials >> Amino compound >> Amide compound
• Name: N-(2-Bromo-5-methoxyphenyl)acetamide
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• CAS Registry Number: 123027-99-6
• SMILES: CC(=O)NC1=C(C=CC(=C1)OC)Br

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P280-P301+P312-P302+P352-P305+P351+P338

Discovory and Applicatios

N-(2-bromo-5-methoxyphenyl)acetamide is an organic compound that has found wide applications in pharmaceutical research and organic synthesis due to its unique structure and chemical properties. N-(2-bromo-5-methoxyphenyl)acetamide, with the chemical formula C9H10BrNO2, was first synthesized in the late 20th century during the development of new heterocyclic compounds for medicinal chemistry. Researchers created compounds with potential pharmacological activity by modifying the phenylacetamide backbone with different substituents. Bromine and methoxy groups were introduced to enhance the reactivity and biological activity of the compounds.

The compound is white to off-white crystals. It has moderate solubility in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but limited solubility in water. The presence of bromine and methoxy groups on the benzene ring significantly affects its electronic properties, making it a valuable intermediate in various chemical reactions.

The main use of N-(2-bromo-5-methoxyphenyl)acetamide is in pharmaceutical research. It is a building block for the synthesis of various biologically active molecules. The compound's structural features allow it to participate in the formation of a wide range of drugs, including those with potential anti-inflammatory, antimicrobial, and anticancer properties.

In organic synthesis, N-(2-bromo-5-methoxyphenyl)acetamide is used as an intermediate in the construction of more complex molecules. Its reactivity makes it suitable for a variety of transformations, including nucleophilic substitution and coupling reactions. These properties can be used to synthesize heterocyclic compounds, which are common in medicinal chemistry.

Recent research has explored the use of N-(2-bromo-5-methoxyphenyl)acetamide in materials science. It has been studied for its potential to create new organic materials with unique optical and electronic properties. These materials can be used to develop organic semiconductors, light-emitting diodes (LEDs), and other advanced technologies.

The compound is also used as a chemical probe in biological research. Its ability to interact with specific biomolecules makes it valuable in studying biological pathways and identifying potential drug targets. Researchers use it to study enzyme activity, protein interactions, and cell signaling mechanisms.

In agricultural chemistry, N-(2-bromo-5-methoxyphenyl)acetamide is considered a potential lead compound for the development of new agrochemicals. Its biological activity suggests that it could be used to create herbicides, fungicides, or insecticides that target specific pests or pathogens while minimizing environmental impact.

Ongoing research continues to discover new applications and improve the efficiency of N-(2-bromo-5-methoxyphenyl)acetamide in a variety of fields. Innovations in synthetic methods and materials science are expected to expand its uses, providing new opportunities for its use in advanced technologies and medicines.