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Dodecanamine
[CAS# 124-22-1]

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Identification
Classification Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Amine
Name Dodecanamine
Synonyms Lauramine
Molecular Structure CAS # 124-22-1, Dodecanamine, Lauramine
Molecular Formula C12H27N
Molecular Weight 185.35
CAS Registry Number 124-22-1
EC Number 204-690-6
SMILES CCCCCCCCCCCCN
Properties
Density 0.806
Melting point 28-32 ºC
Boiling point 247-249 ºC
Refractive index 1.4421
Water solubility 78 mg/L (25 ºC)
Flash point 115 ºC
Safety Data
Hazard Symbols symbol symbol symbol symbol   GHS05;GHS07;GHS08;GHS09 Danger    Details
Hazard Statements H290-H302-H304-H314-H318-H335-H372-H400-H410    Details
Precautionary Statements P234-P260-P261-P264-P264+P265-P270-P271-P273-P280-P301+P316-P301+P317-P301+P330+P331-P302+P361+P354-P304+P340-P305+P354+P338-P316-P317-P319-P321-P330-P331-P363-P390-P391-P403+P233-P405-P406-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Acute hazardous to the aquatic environmentAquatic Acute1H400
Skin corrosionSkin Corr.1BH314
Specific target organ toxicity - repeated exposureSTOT RE2H373
Specific target organ toxicity - single exposureSTOT SE3H335
Aspiration hazardAsp. Tox.1H304
Chronic hazardous to the aquatic environmentAquatic Chronic1H410
Substances or mixtures corrosive to metalsMet. Corr.1H290
Acute toxicityAcute Tox.4H302
Serious eye damageEye Dam.1H318
Skin corrosionSkin Corr.1AH314
Chronic hazardous to the aquatic environmentAquatic Chronic2H411
Acute toxicityAcute Tox.4H332
Skin corrosionSkin Corr.1CH314
Skin corrosionSkin Corr.1H314
Acute toxicityAcute Tox.4H312
Transport Information UN 3259
SDS Available
up Discovory and Applicatios
Dodecylamine, also known as laurylamine, is a long-chain primary amine with the chemical formula C12H27N. The discovery of dodecylamine is closely related to the study of fatty amines, which are derivatives of fatty acids. These compounds were first isolated during the development of organic chemistry and the study of natural fats and oils in the late 19th and early 20th centuries. The synthesis of dodecylamine involves the hydrogenation of lauric acid, a fatty acid commonly found in coconut and palm kernel oils, followed by amination.

Dodecylamine is a colorless to pale yellow liquid or solid, depending on the temperature, with an amine-like odor. It has a melting point of 28-30°C and a boiling point of 247°C. Dodecylamine is soluble in organic solvents such as alcohols and ethers, but slightly soluble in water. Its long hydrocarbon chain and amine group make it both hydrophobic and hydrophilic, making it a versatile compound in a variety of applications.

Dodecylamine is widely used in the production of surfactants and emulsifiers. It is a key ingredient in detergent formulations, helping to reduce the surface tension of water and enhance the cleaning ability of detergents. Its ability to form micelles is able to capture and remove grease and dirt. In the food and cosmetics industry, dodecylamine derivatives are used as emulsifiers to stabilize oil and water mixtures, ensuring uniform consistency and texture in products such as lotions, creams, and food emulsions.

Dodecylamine is used as a corrosion inhibitor in various industries. In the oil and gas industry, it is added to pipelines and storage tanks to prevent corrosion of metal surfaces caused by water and acidic components in crude oil. It forms a protective film on metal surfaces, reducing the rate of corrosion. It is also used in water treatment facilities to protect equipment from corrosion and extend the service life of machinery and infrastructure.

Dodecylamine is the basis of chemical synthesis. It is used to synthesize a variety of organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals. Its amine group enables it to participate in various chemical reactions such as amide formation, alkylation, and acylation. Dodecylamine is used as a ligand in catalytic processes, coordinating with metal ions to form complexes that promote chemical reactions.

Dodecylamine and its derivatives have antimicrobial properties. It is used as a biocide in industrial and consumer products to prevent the growth of bacteria, fungi, and algae. This makes it valuable in applications such as cooling tower treatment, paints and coatings. Its antimicrobial properties also make it suitable for use in disinfectants and biocides, helping to control the spread of harmful microorganisms.

In the mining industry, dodecylamine is used as a flotation agent. It is used in the flotation process to separate valuable minerals from ores. Dodecylamine adsorbs to the surface of the mineral, increasing its hydrophobicity, allowing it to be separated from the slurry in the flotation tank.

Dodecylamine should be handled with care as it can be a health hazard. Protective gloves, goggles and protective clothing should be worn to prevent skin and eye contact. Adequate ventilation must be provided to avoid inhalation of vapors. It should be stored in a cool, dry place away from sources of ignition and incompatible materials such as strong oxidants.

Dodecylamine can be harmful to the environment. It is toxic to aquatic life and should be prevented from entering waterways. Proper disposal methods and spill control measures are essential to minimize its impact on the environment. Although it is biodegradable, its release into the environment should still be controlled to prevent ecological damage.
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