Bisindolylmaleimide I
[CAS# 133052-90-1]

Identification

• Classification: Biochemical >> Inhibitor >> TGF-beta/Smad signaling pathway inhibitor (TGF-beta/Smad) >> PKC inhibitor
• Name: Bisindolylmaleimide I
• Synonyms: 3-[1-[3-(Dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrol-2,5-dione; BIM 1
• Molecular Formula: C₂₅H₂₄N₄O₂
• Molecular Weight: 412.48
• CAS Registry Number: 133052-90-1
• EC Number: 603-702-0

Properties

• Solubility: Insoluble (3.2E^-5 g/L) (25 ºC), Calc.^*
• Density: 1.30±0.1 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 280 ºC (decomp)^**

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2013 ACD/Labs)

^** Barth, Hubert; EP 397060 A2 1990.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302