Calcium Citrate Malate Fine Granular
[CAS# 142606-53-9]

Identification

• Classification: Surfactant >> Anionic surfactant >> Fatty acid salt type
• Name: Calcium Citrate Malate Fine Granular
• Synonyms: 2-Hydroxy-1,2,3-propanetricarboxylic acid calcium salt mixt. with hydroxybutanedioic acid calcium salt
• Molecular Formula: C₆H₆O₇^.C₄H₆O₅^.Ca
• Molecular Weight: 364.27
• CAS Registry Number: 142606-53-9
• SMILES: C(C(C(=O)[O-])O)C(=O)[O-].C(C(=O)O)C(CC(=O)O)(C(=O)O)O.[Ca+2]

Discovory and Applicatios

Calcium citrate malate (CCM) is a blend of calcium citrate and calcium malate. It was first developed as a calcium supplement in the late 20th century by researchers seeking to improve calcium absorption and bioavailability. Studies have found that the combination of calcium citrate and calcium malate enhances calcium solubility and absorption in the body, making it an effective dietary calcium source.

Calcium citrate malate is widely used as a dietary supplement to meet the body's calcium needs and support bone health. It is a bioavailable calcium source that is easily absorbed by the intestines, making it suitable for people with low stomach acid or gastrointestinal problems. Calcium citrate malate supplements are available in a variety of forms, including tablets, capsules, and powders.

Calcium citrate malate plays an important role in the prevention and treatment of osteoporosis, a disease characterized by weak and brittle bones. Adequate intake of calcium, along with other bone-supporting nutrients such as vitamin D, magnesium, and vitamin K, helps maintain bone density and reduce the risk of fractures. Calcium citrate malate supplements are recommended for people at risk for osteoporosis, including postmenopausal women and older adults.

Calcium citrate malate is used in antacid formulations to neutralize stomach acid and relieve symptoms such as acid reflux, heartburn, and indigestion. Its alkalinity helps buffer excess stomach acid and relieve gastrointestinal discomfort. Calcium citrate malate-based antacids are sold over the counter in the form of chewable tablets or liquid suspensions to relieve symptoms of acid-related digestive issues.

Calcium citrate malate is added to fortified foods and beverages to increase their calcium content and improve their nutritional value. It is often added to dairy alternatives, fortified juices, breakfast cereals, and baked goods to increase calcium intake, especially for people with lactose intolerance or those who limit dairy consumption. Calcium-fortified products help ensure overall dietary calcium intake and support bone health.

Calcium citrate malate is used in sports nutrition supplements to promote bone health and muscle function in athletes and fitness enthusiasts. Adequate calcium intake is essential for maintaining bone density and preventing stress fractures, especially during high-intensity exercise and endurance activities. Calcium citrate malate supplements are used in sports nutrition formulas to optimize bone health and performance.

Calcium citrate malate is added to infant formula to provide essential calcium for healthy growth and development of infants and young children. Adequate calcium intake during infancy and childhood is essential for bone mineralization and bone growth. Calcium citrate malate ensures optimal absorption and bioavailability of calcium in infant formula, supporting infants' bone health and overall nutritional status.