2-Methyl-1,2-oxaphospholan-5-one 2-oxide
[CAS# 15171-48-9]

Identification

• Classification: Organic raw materials >> Organic phosphine compound
• Name: 2-Methyl-1,2-oxaphospholan-5-one 2-oxide
• Synonyms: 2-Methyl-1-oxa-2,5-dioxo-2-phospholane; 2-Methyl-2,5-dioxo-1,2-oxaphospholane; Exolit PE 110; Exolit PR 110
• Molecular Formula: C₄H₇O₃P
• Molecular Weight: 134.07
• CAS Registry Number: 15171-48-9
• EC Number: 239-225-6
• SMILES: CP1(=O)CCC(=O)O1

Properties

• Density: 1.3±0.1 g/cm³, Calc.^*,1.26 g/mL
• Melting point: 97-98 ºC
• Index of Refraction: 1.427, Calc.^*
• Boiling Point: 191.6±23.0 ºC (760 mmHg), Calc.^*
• Flash Point: 84.0±42.9 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Discovory and Applicatios

2-Methyl-1,2-oxaphospholan-5-one 2-oxide is a chemical compound belonging to the class of oxaphospholanes, which are five-membered cyclic compounds containing phosphorus and oxygen. The molecular formula of this compound is C5H9O3P. Its unique structure, which features both a carbonyl group and an oxide functionality, has attracted attention in various fields of chemical research. The discovery of 2-methyl-1,2-oxaphospholan-5-one 2-oxide is a part of the broader exploration of phosphorus-containing compounds, which began gaining prominence in the mid-20th century due to their diverse reactivity and potential applications.

The synthesis of 2-methyl-1,2-oxaphospholan-5-one 2-oxide typically involves the reaction of phosphorous compounds with appropriate carbonyl precursors. Various synthetic methodologies have been developed, allowing chemists to obtain this compound through different pathways. The resulting product exhibits interesting chemical properties, particularly due to the presence of the phosphonyl and carbonyl functionalities, which can participate in a range of chemical reactions, making it a valuable intermediate in organic synthesis.

One of the primary applications of 2-methyl-1,2-oxaphospholan-5-one 2-oxide lies in the field of medicinal chemistry. Research has indicated that phosphorus-containing compounds often exhibit biological activity, including antimicrobial, antifungal, and anticancer properties. The unique structure of 2-methyl-1,2-oxaphospholan-5-one 2-oxide allows it to interact with biological targets in innovative ways, potentially leading to the development of new therapeutic agents. Ongoing research is focused on exploring the compound's efficacy and mechanism of action against various diseases, highlighting its potential in drug discovery.

Additionally, 2-methyl-1,2-oxaphospholan-5-one 2-oxide has applications in materials science. Its ability to participate in polymerization reactions enables its incorporation into polymer matrices, potentially enhancing the thermal and mechanical properties of the resulting materials. The introduction of phosphorus into polymers can also improve flame retardancy, making it valuable for applications where fire safety is a concern. Researchers are investigating its use in creating advanced materials for coatings, adhesives, and composites, with an emphasis on developing sustainable and high-performance options.

In the realm of agriculture, phosphorus-containing compounds have been explored for their potential as agrochemicals. 2-Methyl-1,2-oxaphospholan-5-one 2-oxide may serve as a precursor for the development of new pesticides or fertilizers. Its ability to interact with plant systems could lead to improved nutrient uptake or protection against pests and diseases, contributing to sustainable agricultural practices. The ongoing demand for environmentally friendly agrochemical solutions has spurred interest in such compounds, with 2-methyl-1,2-oxaphospholan-5-one 2-oxide being a candidate for further research.

Despite its potential, the safety profile of 2-methyl-1,2-oxaphospholan-5-one 2-oxide must be carefully assessed. As with many phosphorus-containing compounds, there may be concerns regarding toxicity and environmental impact. Regulatory guidelines should be adhered to when handling and using this compound to ensure safety in laboratory and industrial settings.

In summary, 2-methyl-1,2-oxaphospholan-5-one 2-oxide represents a promising compound with applications in medicinal chemistry, materials science, and agriculture. Its discovery and continued exploration underscore the importance of phosphorus-containing compounds in chemical research and their potential to contribute to advancements in various industries. As investigations into its properties and applications progress, this compound may play a significant role in the development of innovative solutions across multiple fields.