Apremilast EP Impurity B
[CAS# 15371-06-9]

Identification

• Name: Apremilast EP Impurity B
• Synonyms: 3-Acetamidophthalic acid;3-(Acetylamino)-1,2-benzenedicarboxylic Acid
• Molecular Formula: C₁₀H₉NO₅
• Molecular Weight: 223.18
• CAS Registry Number: 15371-06-9
• EC Number: 239-404-9
• SMILES: CC(=O)NC1=CC=CC(=C1C(=O)O)C(=O)O

Properties

• Solubility: 1630 mg/L (25 ºC water)
• Density: 1.5±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.659, Calc.^*
• Melting point: 198.96 ºC
• Boiling Point: 470.81 ºC, 518.2±45.0 ºC (760 mmHg), Calc.^*
• Flash Point: 267.2±28.7 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07;GHS08 Warning
• Hazard Statements: H317-H341-H351-H361-H413
• Precautionary Statements: P203-P261-P272-P273-P280-P281-P302+P352-P318-P321-P333+P313-P362+P364-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Chronic hazardous to the aquatic environment	Aquatic Chronic	4	H413
Skin sensitization	Skin Sens.	1	H317
Carcinogenicity	Carc.	2	H351
Germ cell mutagenicity	Muta.	2	H341
Reproductive toxicity	Repr.	2	H361