Tubulysin A
[CAS# 205304-86-5]

Identification

• Classification: Biochemical >> Amino acids and their derivatives >> Glycine derivatives
• Name: Tubulysin A
• Synonyms: (alphaS,gammaR)-gamma-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-a-methyl-Benzenepentanoic acid
• Molecular Formula: C₄₃H₆₅N₅O₁₀S
• Molecular Weight: 844.07
• CAS Registry Number: 205304-86-5
• EC Number: 633-790-6

Properties

• Solubility: Sparingly Soluble (0.037 g/L) (25 ºC), Calc.^*
• Density: 1.195±0.06 g/cm³ (20 ºC 760 Torr), Calc.^*
• Melting point: 106-108 ºC (Solv: methanol)^**
• Boiling point: 979.9±65.0 ºC (760 Torr), Calc.^*
• Flash point: 546.4±34.3 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software V11.02 (©1994-2021 ACD/Labs)

^** Steinmetz, Heinrich; Angewandte Chemie, International Edition 2004, V43(37), P4888-4892, S4888/1-S4888/6 CAPLUS.

Safety Data

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	3	H331
Acute toxicity	Acute Tox.	3	H311
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute toxicity	Acute Tox.	3	H301
Eye irritation	Eye Irrit.	2	H319