2-n-Propyl-1,3-propanediol
[CAS# 2612-28-4]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Alcohol
• Name: 2-n-Propyl-1,3-propanediol
• Synonyms: 2-propylpropane-1,3-diol
• Molecular Formula: C₆H₁₄O₂
• Molecular Weight: 118.17
• CAS Registry Number: 2612-28-4
• SMILES: CCCC(CO)CO

Properties

• Density: 1.0±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.447, Calc.^*
• Boiling Point: 230.0±8.0 ºC (760 mmHg), Calc.^*
• Flash Point: 107.3±13.0 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338

Discovory and Applicatios

2-n-Propyl-1,3-propanediol is a chemical compound belonging to the family of diols, characterized by the presence of two hydroxyl groups (-OH) attached to different carbon atoms within a three-carbon chain. This compound consists of a n-propyl group (C3H7) attached to the second carbon of a propane-1,3-diol backbone, giving it both hydrophobic and hydrophilic properties. These characteristics make 2-n-propyl-1,3-propanediol a useful intermediate in the synthesis of various chemicals, particularly in the development of specialty polymers, surfactants, and other industrial materials.

The discovery of 2-n-propyl-1,3-propanediol is part of broader research into functionalized diols that could be used to modify the properties of materials. While the compound itself was not widely studied until more recently, its structure and properties have attracted attention in the field of materials science. The addition of the n-propyl group enhances the hydrophobicity of the diol, providing a unique balance of solubility and reactivity for its applications.

Synthesis of 2-n-propyl-1,3-propanediol is typically achieved through the reaction of propylene oxide with n-propyl alcohol in the presence of a catalyst. This reaction yields the diol, which can then be purified and used in various applications. The process is relatively straightforward, and the compound can be produced efficiently on an industrial scale.

One of the primary applications of 2-n-propyl-1,3-propanediol is in the production of polyesters and polyurethanes, where it serves as a monomer to impart flexibility and hydrophobicity to the final product. In these applications, the presence of the n-propyl group helps to enhance the mechanical properties and water resistance of the polymers. 2-n-Propyl-1,3-propanediol is used to create materials that are durable, yet lightweight, making it ideal for use in coatings, adhesives, and sealants, where both flexibility and stability are important.

In addition to its use in polymers, 2-n-propyl-1,3-propanediol has been explored for its role in the formulation of surfactants and emulsifiers. The balance between its hydrophobic and hydrophilic parts allows it to act as a stabilizer in emulsions, improving the performance of cleaning agents, detergents, and other industrial formulations. Furthermore, its mild reactivity makes it a useful intermediate in the synthesis of other specialty chemicals.

The compound has also shown potential in the cosmetics and personal care industries. Because of its mild nature and non-toxicity, 2-n-propyl-1,3-propanediol has been studied as a potential ingredient in skin care products, such as moisturizers and cleansers. Its ability to act as a humectant, helping to retain moisture in the skin, makes it an attractive candidate for further investigation in cosmetic formulations.

Research into the applications of 2-n-propyl-1,3-propanediol continues, as its ability to modify the properties of materials and chemicals makes it a valuable compound for developing more sustainable and efficient products. As industries move towards greener solutions, this diol represents a versatile and eco-friendly option for the development of new materials and formulations.