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1,2-Benzisothiazolin-3-one
[CAS# 2634-33-5]

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Complete supplier list of 1,2-Benzisothiazolin-3-one
Identification
Classification Food additive >> Preservative
Name 1,2-Benzisothiazolin-3-one
Synonyms 1,2-Benzisothiazol-3(2H)-one; Benzisothiazolin-3-one; Proxan; Proxel; Proxel XL; Proxil
Molecular Structure CAS # 2634-33-5, 1,2-Benzisothiazolin-3-one, 1,2-Benzisothiazol-3(2H)-one, Benzisothiazolin-3-one, Proxan, Proxel, Proxel XL, Proxil
Molecular Formula C7H5NOS
Molecular Weight 151.18
CAS Registry Number 2634-33-5
EC Number 220-120-9
SMILES C1=CC=C2C(=C1)C(=O)NS2
Properties
Density 1.4±0.1 g/cm3, Calc.*
Melting point 154-158 ºC (Expl.)
Index of Refraction 1.661, Calc.*
* Calculated using Advanced Chemistry Development (ACD/Labs) Software.
Safety Data
Hazard Symbols symbol symbol symbol   GHS05;GHS07;GHS09 Danger    Details
Hazard Statements H302-H315-H317-H318-H400-H410-H411    Details
Precautionary Statements P261-P264-P264+P265-P270-P272-P273-P280-P301+P317-P302+P352-P305+P354+P338-P317-P321-P330-P332+P317-P333+P317-P362+P364-P391-P501    Details
Hazard Classification
up    Details
HazardClassCategory CodeHazard Statement
Acute toxicityAcute Tox.4H302
Skin irritationSkin Irrit.2H315
Serious eye damageEye Dam.1H318
Acute hazardous to the aquatic environmentAquatic Acute1H400
Skin sensitizationSkin Sens.1H317
Chronic hazardous to the aquatic environmentAquatic Chronic2H411
Acute toxicityAcute Tox.2H330
Chronic hazardous to the aquatic environmentAquatic Chronic1H410
Chronic hazardous to the aquatic environmentAquatic Chronic3H412
Skin sensitizationSkin Sens.1AH317
Acute toxicityAcute Tox.1H330
Eye irritationEye Irrit.2H319
Eye irritationEye Irrit.2H318
Transport Information UN 3077
SDS Available
up Discovory and Applicatios
1,2-Benzisothiazolin-3-one (BIT) is an organic compound with the molecular formula C7H5NOS. It is a colorless to pale yellow liquid that is primarily used as a biocide and preservative in various industrial applications. BIT belongs to a class of compounds known as isothiazolones, which are characterized by their ability to inhibit the growth of microorganisms.

The discovery of 1,2-benzisothiazolin-3-one can be traced to research conducted in the late 20th century when the search for effective and environmentally friendly biocides gained importance. BIT was developed as a broad-spectrum antimicrobial agent capable of inhibiting the growth of bacteria, fungi, and algae. It quickly became a valuable alternative to other more hazardous biocides, such as formaldehyde-releasing agents, in industrial formulations.

1,2-Benzisothiazolin-3-one is widely used as a preservative in aqueous formulations, including paints, coatings, adhesives, and personal care products. Its primary application is in water-based formulations, where it helps prevent microbial growth, particularly in products that are prone to contamination, such as cosmetics, household cleaners, and detergents. The compound is effective against a broad spectrum of microorganisms, including bacteria, yeasts, and molds, making it highly versatile in the preservation of various products.

In addition to its use in personal care and household products, BIT is commonly used in industrial applications such as cooling tower water treatment, oilfield chemicals, and in the paper and textile industries. In these industries, BIT serves as a preservative to prevent the growth of bacteria and fungi in industrial fluids and other aqueous systems. It is often incorporated into formulations for use in systems where microbial contamination could lead to issues such as foul odors, product degradation, or reduced system efficiency.

BIT has also been investigated for its role in preventing the growth of algae in water treatment systems, and it is commonly added to formulations for algae control in swimming pools and water reservoirs. The compound's efficacy in inhibiting microbial growth at low concentrations, combined with its relatively low toxicity compared to some other biocides, has made it a widely used agent in the formulation of preservatives for various industrial and consumer products.

In summary, 1,2-benzisothiazolin-3-one is a versatile and widely used biocide that serves as an effective preservative in a range of industrial and consumer products. Its discovery as a potent antimicrobial agent has led to its widespread use in the preservation of water-based formulations, and its ability to inhibit bacterial, fungal, and algal growth has made it an important compound in industries such as personal care, paints, coatings, and water treatment.
Market Analysis Reports
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