Dexamethasone phosphate
[CAS# 312-93-6]

Identification

• Classification: API >> Hormone and endocrine-regulating drugs >> Adrenal corticosteroids
• Name: Dexamethasone phosphate
• Synonyms: [2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] dihydrogen phosphate
• Molecular Formula: C₂₂H₃₀FO₈P
• Molecular Weight: 472.44
• CAS Registry Number: 312-93-6
• EC Number: 206-232-0
• SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COP(=O)(O)O)O)C)O)F)C

Properties

• Solubility: 394.3 mg/L (25 ºC water)
• Density: 1.5±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.594, Calc.^*
• Melting point: 90.27 ºC
• Boiling Point: 480.00 ºC, 669.6±65.0 ºC (760 mmHg), Calc.^*
• Flash Point: 358.7±34.3 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS08 Warning
• Hazard Statements: H361
• Precautionary Statements: P201-P202-P280-P308+P313-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Reproductive toxicity	Repr.	2	H361
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Specific target organ toxicity - repeated exposure	STOT RE	2	H373