Indometacin
[CAS# 53-86-1]

Identification

• Classification: API >> Antipyretic analgesics >> Non-steroidal anti-inflammatory drugs
• Name: Indometacin
• Synonyms: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid
• Molecular Formula: C₁₉H₁₆ClNO₄
• Molecular Weight: 357.79
• CAS Registry Number: 53-86-1
• EC Number: 200-186-5

Properties

• Melting point: 155-162 ºC

Safety Data

• Hazard Symbols: T+
• Risk Codes: R28
• Safety Description: S28;S36/37;S45

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	1	H300
Acute toxicity	Acute Tox.	2	H300
Skin sensitization	Skin Sens.	1	H317
Reproductive toxicity	Repr.	1B	H360
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Serious eye damage	Eye Dam.	1	H318
Chronic hazardous to the aquatic environment	Aquatic Chronic	4	H413
Specific target organ toxicity - single exposure	STOT SE	3	H335
Acute toxicity	Acute Tox.	3	H301
Respiratory sensitization	Resp. Sens.	1	H334
Acute toxicity	Acute Tox.	1	H310
Reproductive toxicity	Repr.	1A	H360
Reproductive toxicity	Lact.	-	H362
Reproductive toxicity	Repr.	2	H361
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Acute toxicity	Acute Tox.	3	H311
Reproductive toxicity	Repr.	1B	H360FD
Germ cell mutagenicity	Muta.	2	H341
Chronic hazardous to the aquatic environment	Aquatic Chronic	2	H411

• Transport Information: UN 2811