Palbociclib Impurity 16
[CAS# 571189-64-5]

Identification

• Name: Palbociclib Impurity 16
• Synonyms: 6-acetyl-2-amino-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one
• Molecular Formula: C₁₅H₁₈N₄O₂
• Molecular Weight: 286.33
• CAS Registry Number: 571189-64-5
• SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)N)C3CCCC3)C(=O)C

Properties

• Solubility: 49.56 mg/L (25 ºC water)
• Density: 1.3±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.635, Calc.^*
• Melting point: 199.43 ºC
• Boiling Point: 471.82 ºC, 531.7±60.0 ºC (760 mmHg), Calc.^*
• Flash Point: 275.4±32.9 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501