Sorafenib Carboxylic Acid Methyl Ester
[CAS# 573673-43-5]

Identification

• Name: Sorafenib Carboxylic Acid Methyl Ester
• Synonyms: Methyl 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinate
• Molecular Formula: C₂₁H₁₅ClF₃N₃O₄
• Molecular Weight: 465.81
• CAS Registry Number: 573673-43-5
• SMILES: COC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

Properties

• Solubility: 0.06827 mg/L (25 ºC water)
• Density: 1.5±0.1 g/cm³, Calc.^*
• Index of Refraction: 1.619, Calc.^*
• Melting point: 236.71 ºC
• Boiling Point: 551.61 ºC, 494.5±45.0 ºC (760 mmHg), Calc.^*
• Flash Point: 252.8±28.7 ºC, Calc.^*

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501