Dimepranol acedoben
[CAS# 61990-51-0]

Identification

• Classification: Organic raw materials >> Amino compound >> Amide compound
• Name: Dimepranol acedoben
• Synonyms: NSC 59001; 1-(Dimethylamino)-2-propanol 4-(acetylamino)benzoate (salt)
• Molecular Formula: C₉H₉NO₃^.C₅H₁₃NO
• Molecular Weight: 282.34
• CAS Registry Number: 61990-51-0
• EC Number: 263-361-5
• SMILES: CC(CN(C)C)O.CC(=O)NC1=CC=C(C=C1)C(=O)O

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H315-H319-H335
• Precautionary Statements: P261-P264-P264+P265-P271-P280-P302+P352-P304+P340-P305+P351+P338-P319-P321-P332+P317-P337+P317-P362+P364-P403+P233-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315
Specific target organ toxicity - single exposure	STOT SE	3	H335

Discovory and Applicatios

Dimepranol acedoben is a chemical substance that has attracted attention for its potential therapeutic applications. It is primarily used as a pharmaceutical compound, noted for its role as an adrenergic drug. Dimepranol acedoben combines two distinct components: dimepranol, which has sympathomimetic properties, and acedoben, a chemical moiety that modulates the drug's overall effect. This combination makes it useful in various medical conditions where enhancement of certain physiological responses is required.

The discovery of dimepranol acedoben dates back to the research focused on improving adrenergic drugs, particularly those targeting cardiovascular and respiratory systems. The development of dimepranol acedoben was driven by the desire to create a compound with greater selectivity and fewer side effects compared to previous adrenergic agents. This led to extensive modifications of existing drug structures, with the goal of optimizing efficacy and safety. The synthesis of dimepranol acedoben followed the tradition of chemical innovation in the 20th century, where combining known functional groups allowed for the development of drugs with novel therapeutic potential.

Dimepranol acedoben is primarily used in the treatment of conditions involving respiratory and circulatory systems, particularly in cases requiring bronchodilation and improved blood circulation. Its sympathomimetic action helps in promoting smooth muscle relaxation, particularly in the airways, thus improving breathing in patients suffering from conditions like asthma or chronic obstructive pulmonary disease (COPD). The drug also has applications in improving circulation, making it useful in treating cardiovascular issues such as hypotension (low blood pressure) and poor peripheral blood flow. By stimulating specific adrenergic receptors, dimepranol acedoben can increase heart rate and blood vessel constriction, thereby aiding in the restoration of normal circulation.

In addition to its primary use in the respiratory and cardiovascular systems, dimepranol acedoben has been investigated for its broader applications in clinical medicine. It is part of a group of drugs that are often employed to improve the general condition of patients undergoing surgery or those suffering from acute conditions requiring immediate circulatory support. The drug is also used in some cases as an adjunct treatment in neurological disorders, where its ability to modulate the autonomic nervous system provides additional therapeutic benefits.

Despite its promising applications, the use of dimepranol acedoben is not without risks. As with many adrenergic agents, it can cause side effects related to overstimulation of the sympathetic nervous system, including tachycardia (increased heart rate), hypertension (high blood pressure), and anxiety. Due to these potential side effects, it is important for healthcare providers to carefully monitor patients on this medication, particularly in those with pre-existing heart conditions or hypertension.

As research into the pharmacodynamics and pharmacokinetics of dimepranol acedoben continues, there may be further refinements in its use. New formulations or combinations with other drugs might improve its efficacy and reduce adverse effects, expanding its potential in both clinical and emergency care settings.

In summary, dimepranol acedoben is a specialized pharmaceutical compound that plays an important role in the management of respiratory and cardiovascular conditions. It exemplifies the continued evolution of adrenergic drugs and their applications in modern medicine, offering potential benefits in improving circulation and lung function. With careful use, it remains an important part of the therapeutic arsenal for treating conditions involving poor circulation and respiratory distress.

References

1985. [Duration of the cultivation of cell cultures of chick embryo fibroblasts in the presence of isoprinosine]. Acta microbiologica Bulgarica.
URL: 2422882