Captopril
[CAS# 62571-86-2]

Identification

• Classification: API >> Circulatory system medication >> Antihypertensive drug
• Name: Captopril
• Synonyms: (2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline; (S,S)-1-(D-3-Mercapto-2-methyl-1-oxopropyl)-L-proline
• Molecular Formula: C₉H₁₅NO₃S
• Molecular Weight: 217.28
• CAS Registry Number: 62571-86-2
• EC Number: 263-607-1

Properties

• Melting point: 103-108 ºC
• alpha: -129.5 º (c=1, EtOH)
• Water solubility: soluble

Safety Data

• Hazard Symbols: Xi
• Risk Codes: R36/37/38
• Safety Description: S26;S37/39

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Skin sensitization	Skin Sens.	1	H317
Reproductive toxicity	Repr.	1A	H360
Reproductive toxicity	Repr.	2	H361
Serious eye damage	Eye Dam.	1	H318
Reproductive toxicity	Repr.	1B	H360
Specific target organ toxicity - single exposure	STOT SE	3	H335
Eye irritation	Eye Irrit.	2	H319
Reproductive toxicity	Lact.	-	H362
Skin irritation	Skin Irrit.	2	H315
Acute toxicity	Acute Tox.	4	H312
Acute toxicity	Acute Tox.	4	H302
Reproductive toxicity	Repr.	1B	H360F
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Acute toxicity	Acute Tox.	4	H332
Germ cell mutagenicity	Muta.	2	H341