N,N-Dimethyl-N',N'-bis(2-hydroxypropyl)-1,3-propanediamine
[CAS# 63469-23-8]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Amine
• Name: N,N-Dimethyl-N',N'-bis(2-hydroxypropyl)-1,3-propanediamine
• Synonyms: N,N-Di(2-hydroxypropyl)-N',N'-dimethyl-1,3-propanediamine; N,N-Dimethyl-N',N'-di(2-hydroxypropyl)-1,3-propanediamine; N-(3-Dimethylaminopropyl)-N,N-diisopropanolamine; PC CAT NP 10; PE 4360
• Molecular Formula: C₁₁H₂₆N₂O₂
• Molecular Weight: 218.34
• CAS Registry Number: 63469-23-8
• EC Number: 264-261-4
• SMILES: CC(CN(CCCN(C)C)CC(C)O)O

Properties

• Density: 0.990

Safety Data

• Hazard Symbols: GHS05 Danger
• Hazard Statements: H314-H318-H412
• Precautionary Statements: P260-P264-P264+P265-P273-P280-P301+P330+P331-P302+P361+P354-P304+P340-P305+P354+P338-P316-P317-P321-P363-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Serious eye damage	Eye Dam.	1	H318
Skin corrosion	Skin Corr.	1C	H314
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Skin corrosion	Skin Corr.	1B	H314
Skin irritation	Skin Irrit.	2	H315

• Transport Information: UN 2375

Discovory and Applicatios

N,N-Dimethyl-N',N'-bis(2-hydroxypropyl)-1,3-propanediamine, commonly known as DMHPDA, is an important chemical compound in the realm of organic chemistry and material science. Its discovery and development have paved the way for a range of applications due to its unique chemical properties and versatility.

Discovered in the mid-20th century, DMHPDA is a diol-functionalized diamine that features two hydroxyl groups and two dimethylamino groups attached to a 1,3-propanediamine backbone. This structural arrangement gives DMHPDA a high degree of reactivity and solubility, making it useful in various industrial and scientific applications.

One of the primary applications of DMHPDA is in the field of polymer chemistry. Its dual functional groups allow it to act as a crosslinking agent or a hardener in the production of polymers and resins. When used in combination with epoxy resins, DMHPDA can enhance the mechanical properties of the final material, such as its strength and thermal stability. This makes it valuable in the manufacturing of high-performance coatings, adhesives, and composite materials.

In addition to its role in polymer chemistry, DMHPDA is employed in the production of chelating agents and corrosion inhibitors. The hydroxyl and amino groups in DMHPDA can form complex coordination compounds with metal ions, making it effective in sequestering metals and preventing corrosion in various industrial processes. This property is particularly useful in the formulation of industrial cleaners and rust inhibitors.

DMHPDA also finds applications in the pharmaceutical and medical fields. Its ability to form stable complexes with metal ions and its solubility in water make it a useful ingredient in drug formulations and delivery systems. The compound's functionality can be exploited to improve the solubility and bioavailability of certain drugs, facilitating more effective therapeutic interventions.

The compound's reactivity and versatility extend to its use as a ligand in organometallic chemistry. Its ability to coordinate with transition metals makes it valuable in the synthesis of metal-organic frameworks and catalysts for various chemical reactions. These applications are important in the development of new materials and catalytic processes that have broad implications for chemical manufacturing and environmental management.

Despite its diverse applications, the use of DMHPDA must be managed with care due to potential health and safety considerations. As with many chemical substances, appropriate safety protocols should be followed during its handling and use to minimize risks.