4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole
[CAS# 656825-76-2]

Identification

• Classification: Organic raw materials >> Organic fluorine compound
• Name: 4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole
• Molecular Formula: C₇H₆ClF₅N₂O
• Molecular Weight: 264.58
• CAS Registry Number: 656825-76-2
• SMILES: FC(C1=NN(C)C(OC(F)F)=C1CCl)(F)F

Safety Data

• Hazard Symbols: GHS05;GHS07 Danger
• Hazard Statements: H302-H314
• Precautionary Statements: P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501
• Transport Information: UN 3265

Discovory and Applicatios

4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole is a chemical compound with a complex structure that incorporates several functional groups, making it highly relevant in various areas of research and application. This compound belongs to the pyrazole family, which is known for its diverse biological and chemical properties. The presence of both fluorine and chlorine atoms in its structure significantly enhances its chemical reactivity and stability, making it a valuable component in the development of advanced materials and pharmaceutical products.

The discovery of 4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole can be traced to studies focused on fluorine chemistry and its applications in drug development and materials science. The introduction of fluorine atoms into organic compounds is known to alter their chemical properties, such as lipophilicity and metabolic stability, which is particularly useful in pharmaceutical chemistry. The compound’s unique structure, with a combination of electron-withdrawing groups like trifluoromethyl and difluoromethoxy, has made it an interesting subject of research in medicinal chemistry and agrochemicals.

In pharmaceutical development, compounds like 4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole are of interest due to their potential to act as inhibitors or modulators of specific biological pathways. The trifluoromethyl group in particular has been shown to enhance the binding affinity of molecules to biological targets, making them potent candidates for drug discovery. Researchers have investigated its application as a possible scaffold for designing new therapeutic agents, especially in the treatment of diseases related to inflammation, cancer, and infectious diseases. The fluorinated nature of the compound also suggests it may have enhanced stability in vivo, reducing the need for frequent administration.

In addition to its potential pharmaceutical applications, 4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole has also found uses in the development of agrochemicals. The inclusion of halogen atoms in the molecular structure often confers increased resistance to environmental degradation, making the compound effective as a pesticide or herbicide. The compound’s ability to interact with specific biological systems at a molecular level is beneficial for the selective control of pests and weeds, thereby improving crop yield and reducing the need for toxic or broad-spectrum chemicals.

Furthermore, this compound holds potential in materials science, particularly in the development of functional materials that require stability under extreme conditions. The combination of electronegative fluorine atoms and the pyrazole ring structure offers opportunities in the creation of specialized coatings, adhesives, and polymers. These materials are often used in high-performance applications where durability and resistance to harsh chemicals are essential.

Despite its potential, the full scope of applications for 4-(Chloromethyl)-5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole continues to be explored. Its diverse reactivity and the ability to introduce specific functional groups into its structure make it a promising candidate in fields ranging from pharmaceuticals to industrial applications. As research progresses, the compound's role in developing more efficient, stable, and selective chemical products is expected to expand.