Methyl sulfone
[CAS# 67-71-0]

Identification

• Classification: Organic raw materials >> Organic sulfur compound
• Name: Methyl sulfone
• Synonyms: Dimethyl sulfone; MSM; Methyl sulfonyl methane
• Molecular Formula: C₂H₆O₂S
• Molecular Weight: 94.13
• CAS Registry Number: 67-71-0
• EC Number: 200-665-9
• SMILES: CS(=O)(=O)C

Properties

• Density: 1.1±0.1 g/cm³, Calc.^*, 1.45 g/mL
• Melting point: 110 ºC
• Index of Refraction: 1.402, Calc.^*
• Boiling Point: 240.9±8.0 ºC (760 mmHg), Calc.^*, 238 ºC
• Flash Point: 143.3±0.0 ºC, Calc.^*, 143 ºC

^* Calculated using Advanced Chemistry Development (ACD/Labs) Software.

Safety Data

• Hazard Symbols: GHS07 Warning
• Hazard Statements: H302-H315-H319-H335
• Precautionary Statements: P261-P305+P351+P338

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Eye irritation	Eye Irrit.	2	H319
Skin irritation	Skin Irrit.	2	H315

Discovory and Applicatios

Methyl sulfone, also known as dimethyl sulfone or DMSO2, is an organosulfur compound with the chemical formula C2H6O2S. It is a colorless, odorless solid that is soluble in water and organic solvents. Methyl sulfone has gained attention in various fields due to its unique chemical properties and potential applications.

The discovery of methyl sulfone dates back to the early 20th century when it was first identified as a byproduct of dimethyl sulfoxide (DMSO) oxidation. DMSO is a widely used solvent and has notable biological properties, leading to extensive research on its derivatives, including methyl sulfone. The structural stability and polarity of methyl sulfone make it an interesting subject for further study, leading to its characterization and potential uses in various applications.

Methyl sulfone has garnered significant interest in the pharmaceutical industry due to its purported health benefits. It is considered a natural source of sulfur, which plays a crucial role in numerous biological processes. Methyl sulfone has been investigated for its potential anti-inflammatory and antioxidant properties, making it a candidate for treating conditions such as arthritis and other inflammatory disorders. Additionally, it is thought to support joint health and improve mobility, leading to its use as a dietary supplement in some health products.

In the realm of organic chemistry, methyl sulfone serves as a versatile reagent in various chemical transformations. It is commonly used as a sulfonylating agent, facilitating the introduction of sulfonyl groups into organic molecules. This reactivity allows for the synthesis of sulfonamides and other important compounds, contributing to the development of pharmaceuticals and agrochemicals. Moreover, methyl sulfone can act as a leaving group in certain reactions, further enhancing its utility in synthetic methodologies.

Methyl sulfone is also employed in the production of sulfonated polymers, which have applications in various industrial processes. These polymers are known for their excellent thermal stability and chemical resistance, making them suitable for use in membranes, coatings, and other materials. The incorporation of methyl sulfone into polymer matrices can improve properties such as mechanical strength and resistance to solvents.

Furthermore, methyl sulfone has found applications in the food industry, where it is used as a processing aid and flavor enhancer. Its ability to enhance the solubility of certain compounds makes it valuable in formulating food products and dietary supplements.

Despite its benefits, research on methyl sulfone is still evolving, and ongoing studies aim to better understand its mechanisms of action and potential therapeutic applications. The safety profile of methyl sulfone is generally considered favorable, but comprehensive studies are needed to establish its long-term effects and efficacy in various applications.

In summary, methyl sulfone is a multifaceted compound with diverse applications ranging from pharmaceuticals to industrial processes. Its discovery as a byproduct of dimethyl sulfoxide has paved the way for further research into its properties and potential uses. As interest in this compound continues to grow, it is likely to play an increasingly important role in various fields, contributing to advancements in health, chemistry, and materials science.