1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol
[CAS# 67151-63-7]

Identification

• Classification: Pharmaceutical intermediate >> Heterocyclic compound intermediate >> Pyrimidine compound >> Alcohol
• Name: 1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol
• Molecular Formula: C₁₃H₃₁N₃O
• Molecular Weight: 245.40
• CAS Registry Number: 67151-63-7
• EC Number: 266-587-2
• SMILES: CC(CN(CCCN(C)C)CCCN(C)C)O

Properties

• Density: 0.89
• Boiling point: 290 ºC
• Refractive index: 1.459

Safety Data

• Hazard Symbols: GHS05;GHS07;GHS09 Danger
• Hazard Statements: H302-H312-H314-H318-H332-H372-H412
• Precautionary Statements: P260-P261-P264-P264+P265-P270-P271-P273-P280-P301+P317-P301+P330+P331-P302+P352-P302+P361+P354-P304+P340-P305+P354+P338-P316-P317-P319-P321-P330-P362+P364-P363-P405-P501

Hazard Classification

Hazard	Class	Category Code	Hazard Statement
Acute toxicity	Acute Tox.	4	H302
Serious eye damage	Eye Dam.	1	H318
Skin corrosion	Skin Corr.	1C	H314
Skin corrosion	Skin Corr.	1B	H314
Chronic hazardous to the aquatic environment	Aquatic Chronic	3	H412
Specific target organ toxicity - repeated exposure	STOT RE	2	H373
Acute toxicity	Acute Tox.	4	H332
Acute toxicity	Acute Tox.	4	H312
Specific target organ toxicity - repeated exposure	STOT RE	1	H372
Skin corrosion	Skin Corr.	1A	H314

• Transport Information: UN 2735

Discovory and Applicatios

1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol, also known as bis[3-(dimethylamino)propyl]amino-2-propanol, is a compound with distinct chemical properties that have led to its adoption in various industrial and research applications. This compound is recognized for its role in the synthesis of complex molecules and its utility in specialized chemical processes.

The discovery of 1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol emerged from the need to develop new reagents and catalysts for organic synthesis. Its chemical structure features a central propanol group with two bis[3-(dimethylamino)propyl]amino groups attached. This unique structure provides the compound with distinctive reactivity and versatility, making it valuable in several chemical applications.

One of the primary applications of 1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol is as a reagent in organic synthesis. The compound's structure allows it to act as a nucleophilic catalyst in various chemical reactions, facilitating the formation of complex organic molecules. Its ability to stabilize reactive intermediates and interact with electrophiles makes it a useful tool in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. For example, it has been employed in the synthesis of chiral compounds and in the development of new drug candidates.

In addition to its role in organic synthesis, 1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol is used in the development of specialty polymers and resins. Its chemical properties enable it to act as a cross-linking agent or a functional additive in polymer formulations. The compound's ability to form stable bonds with various polymer matrices results in materials with enhanced properties, such as improved mechanical strength, chemical resistance, and stability.

The compound also finds applications in the field of catalysis. Its structure and reactivity make it suitable for use as a catalyst or a co-catalyst in several chemical transformations. For instance, it can be used in polymerization reactions or in the synthesis of complex organic frameworks. Its catalytic properties contribute to the efficiency and selectivity of these processes, making it a valuable component in both academic research and industrial applications.

Moreover, 1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol has potential applications in the development of new materials and technologies. Its unique chemical structure and reactivity suggest that it could be used in the formulation of advanced materials with specific properties, such as high thermal stability or enhanced electrical conductivity.

Overall, 1-[Bis[3-(dimethylamino)propyl]amino]-2-propanol is a versatile compound with significant applications in organic synthesis, materials science, and catalysis. Its unique chemical properties and reactivity make it a valuable tool in various fields, contributing to advancements in chemical research and industrial applications.